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MAK089

Sigma-Aldrich

γ-Glutamyltransferase (GGT) Activity Colorimetric Assay Kit

sufficient for 100 colorimetric tests

Sinónimos:

GGT Colorimetric Assay Kit

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1 KIT
MXP 12,416.00

MXP 12,416.00

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1 KIT
MXP 12,416.00

About This Item

Código UNSPSC:
12161503
NACRES:
NA.84

MXP 12,416.00

Check Cart for Availability
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uso

sufficient for 100 colorimetric tests

método de detección

colorimetric

enfermedades relevantes

cardiovascular diseases; neurological disorders; cancer; gastrointestinal diseases

temp. de almacenamiento

−20°C

Información sobre el gen

human ... GGT1(2678) , GGT2(728441) , GGT5(2687) , GGT6(124975) , GGT7(2686)
mouse ... GGT1(14598) , GGT5(23887) , GGT6(71522) , GGT7(207182)
rat ... GGT1(116568) , GGT5(29566) , GGT6(408206) , GGT7(156275)

Descripción general

γ-Glutamyltransferase (GGT, EC 2.3.2.2) is a membrane-bound protein that catalyzes the transfer of -glutamyl moieties to acceptor molecules such as amino acids or peptides. GGT plays a key role in the λ-glutamyl cycle, a critical pathway for glutathione homeostasis as well as the detoxification of xenobiotics. Serum GGT levels can be elevated in many pathophysiological conditions such as cardiovascular disease, chronic liver disease, and metabolic syndrome. Elevated serum levels of GGT can also be indicative of oxidative stress.[1]

Aplicación

γ-Glutamyltransferase (GGT) Activity Colorimetric Assay Kit has been used to assess the activity of γ-glutamyltransferase.[2][3]

Características y beneficios

Compatible with high-throughput handling systems.

Idoneidad

Suitable for the measurement of gamma-glutamyl transferase (GGT) in a variety of samples including tissue, cells and serum

Principio

The GGT Activity Colorimetric Assay kit provides a simple and direct procedure for measuring GGT activity in a variety of samples. GGT activity is determined by a coupled enzyme assay, in which the GGT transfers the γ-glutamyl group from the substrate L-γ-Glutamyl-p-nitroanilide, liberating the chromogen p-nitroanilide (pNA, 418 nm) proportional to the GGT present. One unit of GGT is the amount of enzyme that will generate 1.0μmole of pNA per minute at 37 °C.

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

188.6 °F - closed cup

Punto de inflamabilidad (°C)

87 °C - closed cup

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Certificados de análisis (COA)

Lot/Batch Number
8A24K07840
8G08K07840
8D20K07840
7K21K07840
7J30K07840

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