The iron content of this material is 0.12%. This information is reported in the lot specific Certificate of Analysis. Please see the link below to review a sample or lot specific Certificate:
https://www.sigmaaldrich.com/US/en/product/sigma/l4040#product-documentation
L4040
Lactoferrin human
recombinant, expressed in rice, Partially iron saturated, ≥90% (SDS-PAGE)
Sinónimos:
Growth-inhibiting protein 12, Lactotransferrin, Talalactoferrin
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100 MG
MXP 4,529.00
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100 MG
MXP 4,529.00
About This Item
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origen biológico
human
recombinante
expressed in rice
Ensayo
≥70% protein basis (Bradford)
≥90% (SDS-PAGE)
Formulario
powder
técnicas
microbiological culture: suitable
solubilidad
H2O: soluble 10 mg/mL
Nº de acceso UniProt
temp. de almacenamiento
2-8°C
Información sobre el gen
human ... LTF(4057)
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Aplicación
Acciones bioquímicas o fisiológicas
Lactoferrin is an iron binding protein. It is structurally similar to transferrin, the plasma iron transport protein; but lactoferrin has a much higher affinity for iron (250 fold). It is very abundant in colostrum and small amounts can also be found in tears, saliva, mucous secretions and in the secondary granules of neutrophils. It is made by mucosal epithelium and neutrophils and is released by these cells in response to inflammatory stimuli. Bacterial growth is inhibited by its ability to sequester iron and also permeabilize bacterial cell walls by binding to lipopolysaccharides through its N-terminus. Lactoferrin can inhibit viral infection by binding tightly to the viral envelope protein. This prevents cell-virus fusion by blocking the binding domain. Lactoferrin appears to activate host defense systems in part by stimulating the release of interleukin-8, a neutrophil activator. It may also be involved in antibody and interleukin synthesis, lymphocyte proliferation and complement activation.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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Certificados de análisis (COA)
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Could you please specify the % of iron saturation in this product?
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