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L2005

Lactoperoxidase from bovine milk

Name: Lactoperoxidase from bovine milk
Brand: SIGMA
Price: 2942 MXP
Availability: InStock

lyophilized powder (essentially salt-free), ≥200 units/mg protein

Sinónimos:

Donor:hydrogen peroxide oxidoreductase, Peroxidase

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Talla/SKU	Disponibilidad	Precio
5 mg	Disponible para enviar HOYdesdeToluca	MXP 2,942.00
10 mg	Comprobar disponibilidad del carrito	MXP 5,191.00
25 mg	Comprobar disponibilidad del carrito	MXP 10,231.00

Acerca de este artículo

Número CAS:

9003-99-0

NACRES:

NA.54

UNSPSC Code:

12352204

EC Number:

232-668-6

MDL number:

MFCD00131484

Número CE:

1.11.1.7 (BRENDA, IUBMB)

eCl@ss:

32160410

Specific activity:

≥200 units/mg protein

Biological source:

bovine milk

MXP 2,942.00

Disponible para enviar HOYDetalles

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Propiedades

biological source

bovine milk

Quality Segment

200

form

lyophilized powder (essentially salt-free)

specific activity

≥200 units/mg protein

absorbance ratio

A_412/280 nm 0.7-0.9

UniProt accession no.

P80025

storage temp.

−20°C

SMILES string

[O+H2]O[O-]

InChI

1S/H2O3/c1-3-2/h1-2H

InChI key

JSPLKZUTYZBBKA-UHFFFAOYSA-N

Gene Information

cow ... LPO(280844)

Descripción

General description

Lactoperoxidase is a major enzyme present in bovine milk and belongs to the peroxidase family. It is present in both plants and animals. The enzyme structure comprises a single polypeptide chain made up of 612 amino acid residues.

Application

Lactoperoxidase from bovine milk has been used as a standard for milk lactoperoxidase to study the role of H₂O₂ in the inhibition of Staphylococcus aureus growth by Lactococcus garvieae in the presence of lactoperoxidase in raw milk. It has also been used in lactoperoxidase-mediated iodination to prepare radiolabeled peptides.

Biochem/physiol Actions

Lactoperoxidase contributes to the antimicrobial system of milk by inactivating a wide range of micro-organisms. This lactoperoxidase-mediated antimicrobial system is also identified in human secretions such as tear-fluid, saliva, and milk. Lactoperoxidase catalyzes the oxidation of molecules by releasing H2O2. The product exhibits antimicrobial activity.

Lactoperoxidase catalyzes the oxidation of iodide to iodine by hydrogen peroxide. This activity provides a gentle, specific alternative to chloramine T for the radioiodination of proteins and DNA.

Analysis Note

Protein determined by Lowry method.

Other Notes

One unit will oxidize 1.0 μmole of 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) at pH 5.5 at 25 °C.

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Este artículo	77332	SRE0082	P8125
Sigma-Aldrich L2005 Lactoperoxidase from bovine milk	Sigma-Aldrich 77332 Peroxidase from horseradish	Sigma-Aldrich SRE0082 Peroxidasa from horseradish	Sigma-Aldrich P8125 Peroxidasa from horseradish
description lyophilized powder (essentially salt-free), ≥200 units/mg protein	description lyophilized, powder, ~150 U/mg	description For research or further manufacturing use only. Not intended for direct use in humans or animals. Non-TSCA use only in US, Type VI, powder, stabilized, ≥250 units/mg solid (using pyrogallol)	description Type I, essentially salt-free, lyophilized powder, ≥50 units/mg solid (using pyrogallol)
biological source bovine milk	biological source horseradish	biological source -	biological source -
specific activity ≥200 units/mg protein	specific activity ~150 U/mg	specific activity ≥250 units/mg solid (using pyrogallol)	specific activity ≥50 units/mg solid (using pyrogallol)
Gene Information cow ... LPO(280844)	Gene Information -	Gene Information -	Gene Information -
form lyophilized powder (essentially salt-free)	form powder	form powder, stabilized	form essentially salt-free, lyophilized powder
storage temp. −20°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C
UniProt accession no. P80025	UniProt accession no. -	UniProt accession no. -	UniProt accession no. -

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Pictogramas

GHS08

Palabra de advertencia

Danger

Códigos de peligro

H334

Indicaciones de precaución

P261 - P284 - P501

Hazard Classifications

Resp. Sens. 1

Clase de almacenamiento

11 - Combustible Solids

¿Qué está pasando?

WGK 1

EPI (equipos de protección individual)

Eyeshields, Gloves, type N95 (US)

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