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G5011

Sigma-Aldrich

Glucan from baker′s yeast (S. cerevisiae)

≥98.00%

Sinónimos:

Glucosan

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25 MG
MXP 9,805.00
100 MG
MXP 33,211.00

MXP 9,805.00

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25 MG
MXP 9,805.00
100 MG
MXP 33,211.00

About This Item

Número de CAS:
9012-72-0
Número CE:
232-739-1
Número MDL:
MFCD00466924
Código UNSPSC:
12352201
NACRES:
NA.25

MXP 9,805.00

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origen biológico

bakers yeast (S. cerevisiae)

Nivel de calidad

200

Ensayo

≥98.00%

Formulario

powder

color

white to faint yellow

solubilidad

water: 9.80-10.20 mg/mL, turbid, colorless to light yellow

temp. de almacenamiento

2-8°C

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Descripción general

Glucan is a natural polysaccharide.[1] They are carbohydrates forming structural components, which is found in the cell walls of yeast, fungi, seaweed and cereals.[2]

Aplicación

Glucan from baker′s yeast (S. cerevisiae) has been used:
  • for immune stimulation[3]
  • to stimulate mRNA expression of a sigma class glutathione S-transferase (GST) in hemocytes[4]
  • to study its effects in rainbow trout intestinal epithelial cell line (RTgutGC)[5]

Acciones bioquímicas o fisiológicas

Glucan enhances anti-infectious immunity, prevents cancer growth, lowers stress and reduces cholesterol level. It has immunostimulatory property.[2] It maintains blood sugar level and rejuvenates skin.[1]

Nota de preparación

Prepared by the method of Bacon, et al.[6]

Otras notas

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
0000395795
0000424167
0000424167
0000395795
0000411475

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Antonella Torosantucci et al.
The Journal of experimental medicine, 202(5), 597-606 (2005-09-09)
To generate a vaccine to protect against a variety of human pathogenic fungi, we conjugated laminarin (Lam), a well-characterized but poorly immunogenic beta-glucan preparation from the brown alga Laminaria digitata, with the diphtheria toxoid CRM197, a carrier protein used in
A novel LRR and Ig domain-containing protein could function as an immune effector in Crassostrea gigas
Wang X, et al.
Fish & Shellfish Immunology (2019)
Sequence features, expression profiles and biochemical characteristics of a sigma class glutathione S-transferase gene (AiGSTsigma) from bay scallop Argopecten irradians
Wang M, et al.
Invertebrate survival journal , 15(1), 19-30 (2017)
Simone J C F M Moorlag et al.
Cell reports, 31(7), 107634-107634 (2020-05-21)
β-glucan is a potent inducer of epigenetic and functional reprogramming of innate immune cells, a process called "trained immunity," resulting in an enhanced host response against secondary infections. We investigate whether β-glucan exposure confers protection against pulmonary Mycobacterium tuberculosis (Mtb)
Glucan supplementation enhances the immune response against an influenza challenge in mice
Vetvicka V and Vetvickova J
Annals of Translational Medicine, 3(2) (2015)
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Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. What is the solubility of the product?

    1 answer

    1. The solubility of this product can be found on the lot specific Certificate of Analysis. When dissolved in water at a concentration of 9.80 - 10.20 mg/mL, the product forms a turbid solution with visible insoluble particulates, and the solution color ranges from colorless to light yellow.

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