F8384

Flavin adenine dinucleotide disodium salt hydrate

BioReagent, suitable for cell culture

• Sinónimos: FAD, FAD-Na₂, Riboflavin 5′-adenosine diphosphate disodium salt
• Fórmula empírica (notación de Hill): C₂₇H₃₁N₉Na₂O₁₅P₂ · xH₂O
• Número de CAS: 84366-81-4
• Peso molecular: 829.51 (anhydrous basis)
• Beilstein: 5326842
• Número MDL: MFCD08277021
• Código UNSPSC: 12352207
• ID de la sustancia en PubChem: 24894962
• NACRES: NA.75

Propiedades

• origen biológico: bovine milk
• Línea del producto: BioReagent
• Ensayo: ≥95%
• Formulario: powder
• técnicas: cell culture | mammalian: suitable
• solubilidad: water: 50 mg/mL, clear
• temp. de almacenamiento: −20°C
• cadena SMILES: [Na+].[Na+].[H]O[H].Cc1cc2N=C3C(=O)NC(=O)N=C3N(C[C@H](O)[C@H](O)[C@H](O)COP([O-])(=O)OP([O-])(=O)OC[C@H]4O[C@H]([C@H](O)[C@@H]4O)n5cnc6c(N)ncnc56)c2cc1C
• InChI: 1S/C27H33N9O15P2.2Na.H2O/c1-10-3-12-13(4-11(10)2)35(24-18(32-12)25(42)34-27(43)33-24)5-14(37)19(39)15(38)6-48-52(44,45)51-53(46,47)49-7-16-20(40)21(41)26(50-16)36-9-31-17-22(28)29-8-30-23(17)36;;;/h3-4,8-9,14-16,19-21,26,37-41H,5-7H2,1-2H3,(H,44,45)(H,46,47)(H2,28,29,30)(H,34,42,43);;;1H2/q;2*+1;/p-2/t14-,15+,16+,19-,20+,21+,26+;;;/m0.../s1
• Clave InChI: GXTPHHZYFMAGLX-UJXBNFGUSA-L

Descripción

Descripción general

Flavin adenine dinucleotide (FAD) is a redox cofactor of flavoproteins, such as cytochrome-b₅ reductase enzyme.[1] With the help of nicotinamide adenine dinucleotide phosphate (NADPH), FAD can be reduced to form FADH₂.[2]

Aplicación

Flavin adenine dinucleotide (FAD) is used as a redox cofactor (electron carrier) by flavoproteins including succinate dehydrogenase (complex), α-ketoglutarate dehydrogenase, apoptosis-inducing factor 2 (AIF-M2, AMID), folate/FAD-dependent tRNA methyltransferases, and N-hydroxylating flavoprotein monooxygenases. FAD is a component of the pyruvate dehydrogenase complex.

Flavin adenine dinucleotide disodium salt hydrate has been used as a component in the extraction buffer for plant tissue extraction.[3] It has also been used to study its effects on infarct areas of middle cerebral artery occlusion (MCAO) induced mice.[4]

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)