F3418

Monoclonal Anti-Cytokeratin, pan−FITC antibody produced in mouse

clone C-11, purified immunoglobulin, buffered aqueous solution

• Sinónimos: Monoclonal Anti-Pan Cytokeratin
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• conjugado: FITC conjugate
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: C-11, monoclonal
• Formulario: buffered aqueous solution
• reactividad de especies: bovine, mouse, frog, human, kangaroo rat, rat
• condiciones de almacenamiento: protect from light
• técnicas: direct immunofluorescence: 1:50 using PtK₂ cells; immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50 using human placenta; western blot: suitable
• isotipo: IgG1
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: bovine ... Krt1(100301161) ; human ... KRT1(3848) , KRT13(3858) , KRT13(3858) , KRT18(3875) , KRT18(3875) , KRT4(3851) , KRT4(3851) , KRT5(3852) , KRT5(3852) , KRT6A(3868) , KRT6A(3868) , KRT6B(3854) , KRT6B(3854) , KRT8(3856) , KRT8(3856) ; mouse ... Krt1(16678) , Krt10(16661) , Krt10(16661) , Krt13(16663) , Krt13(16663) , Krt18(16668) , Krt18(16668) , Krt4(16682) , Krt4(16682) , Krt5(110308) , Krt5(110308) , Krt6a(16687) , Krt6a(16687) , Krt6b(16688) , Krt6b(16688) , Krt8(16691) , Krt8(16691) ; rat ... Krt1(300250) , Krt1-18(706059) , Krt1-18(706059) , Krt10(450225) , Krt10(450225) , Krt2-5(369017) , Krt2-5(369017) , Krt2-8(25626) , Krt2-8(25626)

Descripción

Descripción general

Cytokeratins are the intermediate filaments of endocrine cells. These proteins belong to the intermediate filament (10 nm) superfamily of cytoskeletal proteins. Cytokeratins are the largest and most complex group of intermediate filaments. The family consists of at least 30 proteins with molecular weights ranging from 40kDa to 68kDa.

Inmunógeno

keratin-enriched preparation from cultured human epidermoid carcinoma cell line A431.

Aplicación

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Immunohistochemistry (1 paper)

Monoclonal Anti-Cytokeratin, pan−FITC antibody has been used in immunocytochemistry and has also been used to visualize lung epithelial cells.

Acciones bioquímicas o fisiológicas

Cytokeratins helps in subtyping several kinds of epithelial differentiation or for narrowing possible sites of origin for metastatic carcinomas. Cytokeratins may play an important role in transhepatic transport and canalicular secretion.

Forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% BSA and 15 mM sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)