E8375

Eserine

• Sinónimos: Physostigmine
• Fórmula empírica (notación de Hill): C₁₅H₂₁N₃O₂
• Número CAS: 57-47-6
• Peso molecular: 275.35
• EC Number: 200-332-8
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277867
• Beilstein/REAXYS Number: 91230
• MDL number: MFCD00151090

Propiedades

• assay: ≥99% (HPLC)
• mp: 102-104 °C (lit.)
• SMILES string: [H][C@]12N(C)CC[C@@]1(C)c3cc(OC(=O)NC)ccc3N2C
• InChI: 1S/C15H21N3O2/c1-15-7-8-17(3)13(15)18(4)12-6-5-10(9-11(12)15)20-14(19)16-2/h5-6,9,13H,7-8H2,1-4H3,(H,16,19)/t13-,15+/m1/s1
• InChI key: PIJVFDBKTWXHHD-HIFRSBDPSA-N
• Gene Information: human ... ACHE(43), APP(351), BCHE(590) ; mouse ... Ache(11423), Bche(12038), Chrm1(12669) ; rat ... Ache(83817), Bche(65036), Chrm2(81645)

Descripción

Biochem/physiol Actions

Acetylcholinesterase inhibitor that crosses the blood-brain barrier and forms a carbamylated enzyme complex with acetyl cholinesterase that degrades slowly.

Acetylcholinesterase inhibitor that crosses the blood-brain barrier.

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Nicotinic) and Acetylcholine Synthesis and Metabolism pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Información de seguridad

• pictograms: GHS06
• signalword: Danger
• hcodes: H300 + H330
• pcodes: P301 + P310 + P330 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Clase de almacenamiento: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges