E3140
5,8,11-Eicosatriynoic acid
≥98%
Sinónimos:
ETI
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About This Item
Fórmula empírica (notación de Hill):
C20H28O2
Número de CAS:
Peso molecular:
300.44
Número MDL:
Código UNSPSC:
12352202
ID de la sustancia en PubChem:
Ensayo
≥98%
Formulario
powder
solubilidad
methanol: 10 mg/mL, clear, colorless to light yellow
temp. de almacenamiento
−20°C
cadena SMILES
CCCCCCCCC#CCC#CCC#CCCCC(O)=O
InChI
1S/C20H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h2-8,11,14,17-19H2,1H3,(H,21,22)
Clave InChI
OWYNLPMPYBYKJP-UHFFFAOYSA-N
Acciones bioquímicas o fisiológicas
The acetylenic analog of 5,8,11-eicosatrienoic acid is an inhibitor of 12-lipoxygenase and, in MDCK cells, triggers release of Ca2+ from endoplasmic reticulum and other intracellular stores.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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G Marone et al.
Journal of clinical & laboratory immunology, 12(2), 111-116 (1983-10-01)
We have studied the role of arachidonic acid (AA) metabolism in the release of lysosomal enzymes (beta-glucuronidase and lysozyme) from human polymorphonuclear leukocytes (PMNs). 5,8,11,14-Eicosatetraenoic acid (ETYA), which inhibits both the cyclo-oxygenase and the lipoxygenase pathways of AA metabolism, was
Qi Wang et al.
PLoS pathogens, 17(1), e1009175-e1009175 (2021-01-12)
The zig-zag model of host-pathogen interaction describes the relative strength of defense response across a spectrum of pathogen-induced plant phenotypes. A stronger defense response results in increased resistance. Here, we investigate the strength of pathogen virulence during disease and place
G Wang et al.
Bone & joint research, 6(7), 452-463 (2017-08-03)
Osteoporosis has become an increasing concern for older people as it may potentially lead to osteoporotic fractures. This study is designed to assess the efficacy and safety of ten therapies for post-menopausal women using network meta-analysis. We conducted a systematic
An inhibitor of lipoxygenase inhibits histamine release from human basophils.
G Marone et al.
Clinical immunology and immunopathology, 17(1), 117-122 (1980-09-01)
Xiaobao Dong et al.
Plant physiology, 167(3), 1186-1203 (2015-01-24)
Pattern-triggered immunity (PTI) and effector-triggered immunity (ETI) are two main plant immune responses to counter pathogen invasion. Genome-wide gene network organizing principles leading to quantitative differences between PTI and ETI have remained elusive. We combined an advanced machine learning method
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