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E006

β-Carboline-3-carboxylic acid N-methylamide

Benzodiazepine receptor inverse agonist, solid

Sinónimos:

β-CCA methylamide, FG-7142, N-Methyl-β-carboline-3-carboxamide

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Tamaño de envaseSKUDisponibilidadPrecio
100 mg
Comprobar disponibilidad del carrito
MXP 6,109.00
500 mg
Comprobar disponibilidad del carrito
MXP 21,098.00

Acerca de este artículo

Fórmula empírica (notación de Hill):
C13H11N3O
Número CAS:
Peso molecular:
225.25
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Form:
solid
Quality level:

MXP 6,109.00


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Nombre del producto

β-Carboline-3-carboxylic acid N-methylamide,

form

solid

Quality Level

color

light tan

solubility

DMSO: >10 mg/mL, H2O: insoluble

SMILES string

CNC(=O)c1cc2c(cn1)[nH]c3ccccc23

InChI

1S/C13H11N3O/c1-14-13(17)11-6-9-8-4-2-3-5-10(8)16-12(9)7-15-11/h2-7,16H,1H3,(H,14,17)

InChI key

QMCOPDWHWYSJSA-UHFFFAOYSA-N

Gene Information

human ... BZRAP1(9256)

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Este artículo
SML2372SML1836G3796
form

solid

form

powder

form

powder

form

solid

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

100

solubility

DMSO: >10 mg/mL, H2O: insoluble

solubility

DMSO: 2 mg/mL, clear

solubility

0.1 M HCl: 2 mg/mL, clear (warmed)

solubility

H2O: >10 mg/mL

color

light tan

color

white to beige

color

white to beige

color

white to off-white

Gene Information

human ... BZRAP1(9256)

Gene Information

-

Gene Information

-

Gene Information

-

Biochem/physiol Actions

Benzodiazepine inverse receptor agonist; potent anxiogenic agent.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Disclaimer

Solutions may be stored for several days at 4 °C.

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Hongrun Yu et al.
PloS one, 7(8), e42684-e42684 (2012-08-29)
Post-traumatic stress disorder (PTSD) is an anxiety disorder that not only affects mental health, but may also affect bone health. However, there have been no studies to examine the direct relationship between PTSD and bone. We employed electric shocks in
Joshua B B Garfield et al.
Behavioral neuroscience, 123(1), 75-85 (2009-01-28)
Six experiments studied the role of GABA-sub(A) receptor activation in expression of overexpectation of Pavlovian fear conditioning. After separate pairings of CSA and CSB with shock in Stage I, rats received pairings of the compound AB with shock in Stage
Natale R Sciolino et al.
Behavioural brain research, 233(1), 191-200 (2012-05-15)
Although exercise improves anxiety in humans, it is controversial whether exercise is anxiolytic in rodents. We tested the hypothesis that stress influences the effect of exercise on anxiety-like and defensive behaviors. To explore the neurobiological mechanisms of exercise, we also
Philip L Johnson et al.
Physiology & behavior, 107(5), 733-742 (2012-05-05)
Although the hypothalamic orexin system is known to regulate appetitive behaviors and promote wakefulness and arousal (Sakurai, 2007 [56]), this system may also be important in adaptive and pathological anxiety/stress responses (Suzuki et al., 2005 [4]). In a recent study
Matthew W Hale et al.
Progress in neuro-psychopharmacology & biological psychiatry, 34(7), 1285-1293 (2010-07-22)
The basolateral amygdala is a nodal structure within a distributed and interconnected network that regulates anxiety states and anxiety-related behavior. Administration of multiple anxiogenic drugs increases cellular responses (i.e., increases c-Fos expression) in a subregion of the basolateral amygdala, but

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Número de artículo de comercio global

SKUGTIN
E006-100MG04061832556413
E006-500MG04061832556420

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