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D9885

Sigma-Aldrich

DEAE-Dextran hydrochloride

powder

Sinónimos:

Diethylaminoethyl-dextran hydrochloride

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About This Item

Número de CAS:
9064-91-9
MDL number:
MFCD00081561
UNSPSC Code:
12352201
NACRES:
NA.25

biological source

bacterial (Leuconostoc mesenteroides)

form

powder

extent of labeling

~3.2% nitrogen

useful pH range

4.0 - 6.0

solubility

H2O: soluble 100 mg/mL, clear, colorless to faintly yellow

storage temp.

room temp

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Application

DEAE-Dextran 500, a polycationic stabilizing molecule and transfection reagent, is used in the development of sustained release protein delivery and nucleic acid transfection systems. DEAE-Dextran 500 may be used for cell immobilization in biosensors.

Preparation Note

Prepared from dextran of average mol. wt. 500,000

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Dextran solution from Leuconostoc mesenteroides 20 % (w/w) (Autoclaved)

Sigma-Aldrich

D8802

Dextran solution from Leuconostoc mesenteroides

Q-Dextran average mol wt 4,000

Sigma-Aldrich

19534

Q-Dextran

DEAE-dextran transfection of mammalian cultured cells.
E T Schenborn et al.
Methods in molecular biology (Clifton, N.J.), 130, 147-153 (1999-12-10)
Anita Bogdanov et al.
Antimicrobial agents and chemotherapy, 58(1), 405-413 (2013-11-06)
Chlamydiae are obligate intracellular bacteria that propagate in the inclusion, a specific niche inside the host cell. The standard method for counting chlamydiae is immunofluorescent staining and manual counting of chlamydial inclusions. High- or medium-throughput estimation of the reduction in
Transfection using DEAE-dextran.
Selden RF.
Current Protocols in Immunology, 10, 10-10 (2001)
Shingo Kikuchi et al.
International journal of pharmaceutics, 386(1-2), 149-155 (2009-11-20)
A multivariate statistical technique was applied to designing a tablet for the sustained release over 24h of diltiazem hydrochloride, a model highly water-soluble drug. Tablets of a hydrophilic matrix composed of dextran derivatives and hypromellose were prepared. The formulations were
Nattamon Niyomdecha et al.
Heliyon, 6(6), e04050-e04050 (2020-06-13)
Niclosamide has been known to inhibit a number of pH-dependent viruses via the neutralization of endosomal acidic pH. It has also been shown to disrupt the mTORC1 signaling pathway. The replication of many viruses requires mTORC1 activation. Here, we investigated
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Contenido relacionado

Dextran and Polysaccharides Overview

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

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