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Merck

D7774

Sigma-Aldrich

Diphenhydramine hydrochloride

analytical standard

Sinónimos:

2-Diphenylmethoxy-N,N-dimethylethylamine hydrochloride, N-(2-Diphenylmethoxyethyl)-N,N-dimethylamine hydrochloride

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About This Item

Fórmula empírica (notación de Hill):
C17H21NO · HCl
Número de CAS:
Peso molecular:
291.82
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

grade

analytical standard

agency

EPA 1694

form

solid

packaging

vial of 250 mg

application(s)

environmental

SMILES string

Cl[H].CN(C)CCOC(c1ccccc1)c2ccccc2

InChI

1S/C17H21NO.ClH/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;/h3-12,17H,13-14H2,1-2H3;1H

InChI key

PCHPORCSPXIHLZ-UHFFFAOYSA-N

Gene Information

human ... HRH1(3269)

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Packaging

Supplied in amber screw-cap vials

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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John W Nichols et al.
Environmental toxicology and chemistry, 34(6), 1425-1435 (2015-04-30)
A need exists to better understand the influence of pH on the uptake and accumulation of ionizable pharmaceuticals in fish. In the present study, fathead minnows were exposed to diphenhydramine (DPH; disassociation constant = 9.1) in water for up to 96 h at
Masaaki Ozawa et al.
Bioorganic & medicinal chemistry letters, 18(14), 3992-3994 (2008-06-24)
An indole alkaloid (hypaphorine (1)) was isolated from Brazilian medicinal plant, Erythrina velutina (Leguminosae). This compound was investigated for sleep promoting effects in mice, and the results showed that it significantly increased non-rapid eye movement (NREM) sleep time during the
Eugene W Schwilke et al.
Journal of forensic sciences, 51(5), 1191-1198 (2006-10-05)
We have previously reported on patterns of drug and alcohol use in fatally injured drivers in Washington State. Here we revisit that population to examine how drug use patterns have changed in the intervening 9 years. Blood and serum specimens
Mohammed Maniruzzaman et al.
International journal of pharmaceutics, 443(1-2), 199-208 (2012-12-25)
The purpose of the study was to investigate and identify the interactions within solid dispersions of cationic drugs and anionic polymers processed by hot-melt extrusion (HME) technique. Propranolol HCl (PRP) and diphenhydramine HCl (DPD) were used as model cationic active
Andreas Papassotiropoulos et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(46), E4369-E4374 (2013-10-23)
In the last decade there has been an exponential increase in knowledge about the genetic basis of complex human traits, including neuropsychiatric disorders. It is not clear, however, to what extent this knowledge can be used as a starting point

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