D7071

Dapoxetine hydrochloride

≥98% (HPLC)

• Sinónimos: (S)-N,N-dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine hydrochloride, S-(+)-N,N-dimethyl-a-[2-(naphthalenyloxy)ethyl] benzenemethanamine hydrochloride, LY-210448 hydrochloride
• Fórmula empírica (notación de Hill): C₂₁H₂₃NO · HCl
• Número de CAS: 129938-20-1
• Peso molecular: 341.87
• Número MDL: MFCD08272809
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 329798842
• NACRES: NA.77

Propiedades

• Ensayo: ≥98% (HPLC)
• Formulario: powder
• actividad óptica: [α]/D +125 to +135°, c = 1 in methanol
• condiciones de almacenamiento: desiccated
• color: white
• solubilidad: DMSO: ≥20 mg/mL
• emisor: Eli Lilly
• temp. de almacenamiento: room temp
• cadena SMILES: Cl.CN(C)[C@@H](CCOc1cccc2ccccc12)c3ccccc3
• InChI: 1S/C21H23NO.ClH/c1-22(2)20(18-10-4-3-5-11-18)15-16-23-21-14-8-12-17-9-6-7-13-19(17)21;/h3-14,20H,15-16H2,1-2H3;1H/t20-;/m0./s1
• Clave InChI: IHWDIQRWYNMKFM-BDQAORGHSA-N
• Información sobre el gen: human ... SLC6A4(6532)

Descripción

Descripción general

Dapoxetine ((+)-(S)-N,N-dimethyl-(α)-[2(1naphthal enyloxy)ethyl]-benzenemethanamine hydrochloride) possess a similar structure as that of fluoxetine.[1]

Acciones bioquímicas o fisiológicas

Dapoxetine is capable of blocking recombinant Kv4.3 potassium voltage-gated channels. It is considered as safe.[1]

Potent Selective serotonin reuptake inhibitor (SSRI); used in treatment of premature ejaculation

Potent and selective SSRI

Características y beneficios

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302,H319,H413
• Consejos de prudencia: P264 - P273 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
• Clasificaciones de peligro: Acute Tox. 4 Oral - Aquatic Chronic 4 - Eye Irrit. 2
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable