D2571

DPPE hydrochloride

≥98% (HPLC)

• Sinónimos: BMS-217380-01, N,N-Diethyl-2-[4-(phenylmethyl) phenoxy]ethanamine hydrochloride, Tesmilifene hydrochloride, YMB1002, [2-(4-Benzyl-phenoxy)-ethyl]-diethyl-amine hydrochloride
• Fórmula empírica (notación de Hill): C₁₉H₂₅NO·HCl
• Número CAS: 92981-78-7
• Peso molecular: 319.87
• NACRES: NA.77
• PubChem Substance ID: 329798745
• UNSPSC Code: 51111800
• MDL number: MFCD11114012
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white
• solubility: H₂O: 16 mg/mL
• storage temp.: 2-8°C
• SMILES string: Cl.CCN(CC)CCOc1ccc(Cc2ccccc2)cc1
• InChI: 1S/C19H25NO.ClH/c1-3-20(4-2)14-15-21-19-12-10-18(11-13-19)16-17-8-6-5-7-9-17;/h5-13H,3-4,14-16H2,1-2H3;1H
• InChI key: TXLHNFOLHRXMAU-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

DPPE is a potent, selective ligand of the microsomal anti-estrogen binding site.

DPPE is a potent, selective ligand of the microsomal anti-estrogen binding site. DPPE is a tamoxifen derivataive that binds with high affinity to the anti-estrogen binding site, but unlike tamoxifen, does not bind to the estrogen receptor. DPPE sensitizes MDR tumor cells to chemotherapy and also inhibits histamine binding at the intracellular histamine site.

Features and Benefits

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable