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C9504

Sigma-Aldrich

Coenzyme Q6

Sinónimos:

2,3-Dimethoxy-5-methyl-6-(farnesylfarnesyl)-1,4-benzoquinone, Ubiquinone-30

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About This Item

Fórmula empírica (notación de Hill):
C39H58O4
Número de CAS:
1065-31-2
Peso molecular:
590.88
MDL number:
MFCD00055698
UNSPSC Code:
12352204
PubChem Substance ID:
24893163

biological source

Saccharomyces cerevisiae

storage temp.

−20°C

SMILES string

COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(\C)C)=C(C)C1=O

Packaging

Sealed ampule.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

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Alejandro Martín-Montalvo et al.
The Biochemical journal, 440(1), 107-114 (2011-08-05)
CoQ(6) (coenzyme Q(6)) biosynthesis in yeast is a well-regulated process that requires the final conversion of the late intermediate DMQ(6) (demethoxy-CoQ(6)) into CoQ(6) in order to support respiratory metabolism in yeast. The gene CAT5/COQ7 encodes the Cat5/Coq7 protein that catalyses
Peter Gin et al.
The Journal of biological chemistry, 278(28), 25308-25316 (2003-05-02)
Coenzyme Q (Q) is a lipid that functions as an electron carrier in the mitochondrial respiratory chain in eukaryotes. There are eight complementation groups of Q-deficient Saccharomyces cerevisiae mutants, designated coq1-coq8. Here we have isolated the COQ6 gene by functional
C J Sippel et al.
The Journal of biological chemistry, 258(2), 1057-1061 (1983-01-25)
Increasing concentrations of glucose (1-5%) in the growth medium depressed ubiquinone-6 biosynthesis in continuously cultured wild type Saccharomyces cerevisiae. In addition, an early intermediate in the pathway of ubiquinone-6 biosynthesis, i.e. 3,4-dihydroxy-5-hexaprenylbenzoate (3,4-DHHB), was found to accumulate. The increase in
S Padilla et al.
Cellular and molecular life sciences : CMLS, 66(1), 173-186 (2008-11-13)
Coenzyme Q is a lipid molecule required for respiration and antioxidant protection. Q biosynthesis in Saccharomyces cerevisiae requires nine proteins (Coq1p-Coq9p). We demonstrate in this study that Q levels are modulated during growth by its conversion from demethoxy-Q (DMQ), a
R R Goewert et al.
Biochemistry, 20(14), 4217-4223 (1981-07-07)
The mutant strain of Saccharomyces cerevisiae E3-24 is unable to synthesize ubiquinone-6. When this mutant is grown in the presence of p-hydroxy[U-14C]benzoate or p-hydroxy[carboxy-14C]benzoate, a radioactive compound accumulates. This new metabolite has been isolated and identified as 3,4-dihydroxy-5-hexaprenylbenzoate (3,4-DHHB). Aerobically
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