Saltar al contenido
Merck
Todas las fotos(4)

Documentos

C8011

Sigma-Aldrich

Chelidamic acid hydrate

≥95%, powder

Sinónimos:

1,4-Dihydro-4-oxo-2,6-pyridinedicarboxylic acid hydrate, 4-Hydroxypyridine-2,6-dicarboxylic acid

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(4)

About This Item

Fórmula empírica (notación de Hill):
C7H5NO5 · xH2O
Número de CAS:
138-60-3
Peso molecular:
183.12 (anhydrous basis)
Beilstein/REAXYS Number:
476229
EC Number:
205-335-8
MDL number:
MFCD03818117
UNSPSC Code:
12352202
PubChem Substance ID:
24278338
NACRES:
NA.77

biological source

synthetic (organic)

assay

≥95%

form

powder

color

brown

mp

267 °C (dec.) (lit.)

solubility

1 M NH4OH: 50 mg/mL, clear to slightly hazy

SMILES string

O.OC(=O)C1=CC(=O)C=C(N1)C(O)=O

InChI

1S/C7H5NO5.H2O/c9-3-1-4(6(10)11)8-5(2-3)7(12)13;/h1-2H,(H,8,9)(H,10,11)(H,12,13);1H2

InChI key

SNGPHFVJWBKEDG-UHFFFAOYSA-N

¿Está buscando productos similares? Visita Guía de comparación de productos

Application

Chelidamic acid hydrate has been used in eluent solution as a complexing additive in high-performance chelation ion chromatography (HPCIC) for speciation of iron. It has also been used as an organic ligand for the polyoxometalate (POM)-based lanthanoid hybrid compounds.

Biochem/physiol Actions

Chelidamic acid (CDA), a hydroxylated derivative of 2,6-pyridine-dicarboxylic acid (DPA), is a trianionic chelating agent.
Among the most potent of the tested "conformationally restricted glutamate analogs" as an inhibitor of glutamate decarboxylase.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Los clientes también vieron

Slide 1 of 2

1 of 2

Diethyl oxalate ≥99%

Sigma-Aldrich

135364

Diethyl oxalate

Phosphorus tribromide 99%

Sigma-Aldrich

256536

Phosphorus tribromide

Chelidamic acid monohydrate: the proton complex of a multidentate ligand
Hall et al.
Acta crystallographica. Section C, Crystal structure communications, 56 (Pt 4), 448-450 (2000-05-18)
Chelidamic acid as a new eluent for the determination of Fe (II) and Fe (III) species and other metals by high performance chelation ion chromatography
Dias J, et al.
Chromatographia null
Construction of a dinuclear cluster containing La (?) and 4-hydroxypyridine-2, 6-dicarboxylic acid to modify Keggin-type polyoxometalate
Taghipour F and Mirzaei M
Journal of Molecular Structure null
Maryam Samaniyan et al.
Dalton transactions (Cambridge, England : 2003), 50(5), 1895-1900 (2021-01-22)
A novel inorganic-organic hybrid, {Na[Tb(L)(H2O)4]3(SiW12O40)}·4H2O, in which L = 4-hydroxypyridine-2,6-dicarboxylic acid (chelidamic acid), was prepared and characterized by elemental analyses, Fourier transform infrared spectroscopy, and single-crystal X-ray diffraction. It consists of a trinuclear terbium cluster bonded to a Keggin-type polyoxotungstate.
T G Porter et al.
Biochemical pharmacology, 34(23), 4145-4150 (1985-12-01)
Twenty conformationally restricted analogues of glutamate including benzoic acids, hydroxy-benzoic acids, pyridine dicarboxylic acids, and pyran dicarboxylic acids were tested as inhibitors of glutamate decarboxylase from rat brain. Chelidonic acid, 2,6-pyridine dicarboxylic acid, chelidamic acid, gallic acid, and 3,4-dihydroxybenzoic acid
Ver todos los artículos relacionados

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico