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C6348

Monoclonal Anti-CXCR2 (IL-8 RB) antibody produced in mouse

Name: Monoclonal Anti-CXCR2 (IL-8 RB) antibody produced in mouse
Brand: SIGMA
Price: 15686 MXP

clone 48311, purified immunoglobulin, lyophilized powder

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Talla/SKU	Disponibilidad	Precio
0.5 mg	Comprobar disponibilidad del carrito	MXP 15,686.00

Acerca de este artículo

UNSPSC Code:

51111800

NACRES:

NA.41

MDL number:

MFCD01864633

Conjugate:

unconjugated

Clone:

48311, monoclonal

Application:

FACS, Neutral

Citations:

MXP 15,686.00

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Propiedades

biological source

mouse

Quality Segment

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

48311, monoclonal

form

lyophilized powder

species reactivity

human

technique(s)

flow cytometry: suitable, neutralization: suitable

isotype

IgG2a

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... IL8RB(3579)
mouse ... Il8rb(12765)

Descripción

General description

The antibody will neutralize human cell surface CXCR-2 mediated-myloperoxidase release from human granulocytes induced by GROα. It will not block myeloperoxidase release induced by IL-8. The antibody reacts with human CXCR-2 transfectant cells and not the parent cell line. The antibody shows no cross-reactivity with CXCR-1.

Immunogen

human CXCR2 transfected NSO mouse myeloma cells.

Biochem/physiol Actions

CXCR2 is a G protein-coupled receptor that binds IL-8 with high affinity. It mediates migration of neutrophils to the sites of inflammation. It also binds CXCL1 and stimulates growth of melanomas.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Preparation Note

Purified using protein G.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Este artículo	C6473	C6223	I2519
Sigma-Aldrich C6348 Monoclonal Anti-CXCR2 (IL-8 RB) antibody produced in mouse	Sigma-Aldrich C6473 Monoclonal Anti-CXCR3 antibody produced in mouse	Sigma-Aldrich C6223 Monoclonal Anti-CXCR-1 (IL-8 RA) antibody produced in mouse	Sigma-Aldrich I2519 Monoclonal Anti-Interleukin-8 antibody produced in mouse
description clone 48311, purified immunoglobulin, lyophilized powder	description clone 49801.111, purified immunoglobulin, lyophilized powder	description clone 42705.111, purified immunoglobulin, lyophilized powder	description clone 6217, purified immunoglobulin, lyophilized powder
species reactivity human	species reactivity human	species reactivity human	species reactivity human
Gene Information human ... IL8RB(3579) mouse ... Il8rb(12765)	Gene Information human ... CXCR3(2833) mouse ... Cxcr3(12766)	Gene Information human ... IL8RA(3577) mouse ... Il8ra(227288)	Gene Information human ... IL8(3576)
biological source mouse	biological source mouse	biological source mouse	biological source mouse
antibody form purified immunoglobulin	antibody form purified immunoglobulin	antibody form purified immunoglobulin	antibody form purified immunoglobulin
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
clone 48311, monoclonal	clone 49801.111, monoclonal	clone 42705.111, monoclonal	clone 6217, monoclonal

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Clase de almacenamiento

11 - Combustible Solids

¿Qué está pasando?

WGK 3

Punto de inflamación (°F)

Not applicable

Punto de inflamación (°C)

Not applicable

EPI (equipos de protección individual)

Eyeshields, Gloves, type N95 (US)

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