This product is soluble in water (1000 mg/mL), in ethanol (20 mg/mL), and in methanol (100 mg/mL).
C4382
Carbamoylcholine chloride
Carbamoylcholine chloride
1 of 2 reviewers received a sample product or took part in a promotion
≥98% (titration), crystalline
Sinónimos:
(2-Hydroxyethyl)trimethylammonium chloride carbamate, Carbachol, Carbamylcholine chloride
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1 G
MXP 3,194.00
10 G
MXP 13,733.00
25 G
MXP 18,990.00
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1 G
MXP 3,194.00
10 G
MXP 13,733.00
25 G
MXP 18,990.00
About This Item
Fórmula lineal:
NH2COOCH2CH2N(Cl)(CH3)3
Número de CAS:
Peso molecular:
182.65
Beilstein/REAXYS Number:
3917459
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
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Quality Level
assay
≥98% (titration)
form
crystalline
color
white
mp
210 °C (dec.) (lit.)
solubility
H2O: 1 g/mL
ethanol: 20 mg/mL
SMILES string
[Cl-].C[N+](C)(C)CCOC(N)=O
InChI
1S/C6H14N2O2.ClH/c1-8(2,3)4-5-10-6(7)9;/h4-5H2,1-3H3,(H-,7,9);1H
InChI key
AIXAANGOTKPUOY-UHFFFAOYSA-N
Gene Information
human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131) , CHRM4(1132) , CHRM5(1133) , CHRNA2(1135)
mouse ... Chrm1(12669)
rat ... Chrm1(25229) , Chrm2(81645) , Chrm3(24260) , Chrna2(170945) , Chrna3(25101) , Chrna4(25590)
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Application
Biochem/physiol Actions
Carbachol elicits tear fluid secretion by interacting with muscarinic receptors.[4] It is an analog of acetylcholine and an antiglaucoma drug. In ciliary processes, carbachol along with nitric oxide (NO) regulates Na+ and K+-ATPase activity.[5] It stimulates insulin vesicles transport to the secretory site to increase insulin secretion.[1]
Non-selective cholinergic agonist that is resistant to the action of cholinesterases; inhibits apoptotic death of cultured neurons, and may induce apoptosis in thymocytes.
Features and Benefits
This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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Los clientes también vieron
Role of the non-neuronal cholinergic system in the eye: a review
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Carbachol and nitric oxide inhibition of Na, K-ATPase activity in bovine ciliary processes
Ellis DZ, et al.
Investigative Ophthalmology & Visual Science, 42(11), 2625-2631 (2001)
Proteomic profiling of tissue-engineered blood vessel walls constructed by adipose-derived stem cells
Wang C, et al.
Tissue Engineering: Part A, 19(3-4), 415-425 (2012)
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Scientific reports, 9(1), 3802-3802 (2019-03-09)
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Goulley J, et al.
Cell Metabolism, 5(3), 207-219 (2007)
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How should Carbamoylcholine chloride, Product C4382, be dissolved?
1 answer-
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What is the difference between Carbamoylcholine chloride Products C4382 and C2409?
1 answer-
C4382 (98%) and C2409 (99%) are the same chemical with slightly different purity specifications. Product No. C2409 is no longer available.
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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