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C4241

Sigma-Aldrich

Anti-Corticotropin-Releasing Factor Receptor 2 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Sinónimos:

Anti-CRFR2

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About This Item

MDL number:
MFCD06798433
UNSPSC Code:
12352203

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 4 μg/mL using human pituitary tissue

UniProt accession no.

Q13324

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CRHR2(1395)
mouse ... Crhr2(12922)
rat ... Crhr2(64680)

Immunogen

synthetic peptide corresponding to the extracellular N-terminal domain of human corticotropin-releasing factor receptor, conjugated to KLH. The immunizing peptide has 100% homology with the rat and mouse gene.

Physical form

Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

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Shaaban A Mousa et al.
Molecular neurobiology, 58(11), 5459-5472 (2021-08-01)
Corticotropin-releasing factor (CRF) orchestrates our body's response to stressful stimuli. Pain is often stressful and counterbalanced by activation of CRF receptors along the nociceptive pathway, although the involvement of the CRF receptor subtypes 1 and/or 2 (CRF-R1 and CRF-R2, respectively)
Shaaban A Mousa et al.
Journal of neuroinflammation, 19(1), 148-148 (2022-06-16)
Under inflammatory conditions, the activation of corticotropin-releasing factor (CRF) receptor has been shown to inhibit pain through opioid peptide release from immune cells or neurons. CRF's effects on human and animal pain modulation depend, however, on the distribution of its

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