C1671

Chlorprothixene hydrochloride

• Sinónimos: 2-Chloro-9-(3-dimethylaminopropylidene)thioxanthene hydrochloride
• Fórmula empírica (notación de Hill): C₁₈H₁₈ClNS · HCl
• Número CAS: 6469-93-8
• Peso molecular: 352.32
• NACRES: NA.77
• PubChem Substance ID: 24278300
• UNSPSC Code: 12352200
• EC Number: 229-289-3
• MDL number: MFCD01941605
• Form: powder

Propiedades

• form: powder
• storage temp.: 2-8°C
• SMILES string: Cl.CN(C)CC\C=C1\c2ccccc2Sc3ccc(Cl)cc13
• InChI: 1S/C18H18ClNS.ClH/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18;/h3-4,6-10,12H,5,11H2,1-2H3;1H/b14-7-;
• InChI key: YWKRLOSRDGPEJR-KIUKIJHYSA-N
• Gene Information: human ... DRD2(1813), DRD3(1814), HTR2A(3356), HTR2C(3358)

Descripción

General description

Chlorprothixene is a neuroleptic drug, which belongs to thioxanthene group. It has anticholinergic effects. Chlorprothixene might be associated with obstructive jaundice and parkinsonism. It is used to treat psychosis.

Application

Chlorprothixene hydrochloride has been used to study its exposure effects on learning and memory of rats.

Biochem/physiol Actions

D₂ dopamine receptor antagonist; blocks a subset of GABA_A receptors in rat cortex that is also blocked by clozapine; thioxanthine antipsychotic.

Información de seguridad

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable