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Merck
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Documentos clave

B8061

Sigma-Aldrich

N-Butyl-N-(4-hydroxybutyl)nitrosamine

ISOPAC®, ≥90% (GC)

Sinónimos:

BBN, N-Butyl-N-butan-4-ol-nitrosamine, N-Butyl-N-nitroso-4-aminobutanol

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About This Item

Fórmula empírica (notación de Hill):
C8H18N2O2
Número de CAS:
Peso molecular:
174.24
MDL number:
UNSPSC Code:
12352116
NACRES:
NA.25

Quality Level

assay

≥90% (GC)

form

liquid

storage temp.

2-8°C

SMILES string

N(N=O)(CCCCO)CCCC

InChI

1S/C8H18N2O2/c1-2-3-6-10(9-12)7-4-5-8-11/h11H,2-8H2,1H3

InChI key

DIKPQFXYECAYPC-UHFFFAOYSA-N

Application

N-Butyl-N-(4-hydroxybutyl)nitrosamine (BBN), a carcinogen, is used to induce histiologically relevant aggressive urinary bladder cancer in animal models.

Biochem/physiol Actions

Carcinogen used to induce urinary bladder cancer in animal models. The result of exposure is histologically comparable to human urinary bladder tumorigenesis. Used in chemopreventative studies.

Packaging

Packaged in a 100 mL serum bottle with butyl rubber stopper and aluminum tear seal.

Caution

Injecting any compatible solvent permits preparation of any desired strength solution without exposure.

Reconstitution

Dissolving the contents in 100 mL of solvent yields a 1% solution.

Legal Information

Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazardExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Carc. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

296.6 °F

flash_point_c

147 °C

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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