FOXD3 is a transcription factor that is involved in maintaining embryonic progenitors in mice. It inhibits interneuron suppression and activate neural crest cell-like phenotype. Rabbit Anti-FOXD3 antibody recognizes canine, bovine, mouse, and human FOXD3.
Immunogen
Synthetic peptide directed towards the middle region of human FOXD3
Application
Rabbit Anti-FOXD3 antibody can be used for western blot applications at a concentration of 2.5μg/ml.
Biochem/physiol Actions
FOXD3 belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined.
Sequence
Synthetic peptide located within the following region: GAYSLAAAAGAAGPYGRPYGLHPAAAAGAYSHPAAAAAAAAAAALQYPYA
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Development (Cambridge, England), 128(21), 4127-4138 (2001-10-31)
The neural crest is a migratory cell population that gives rise to multiple cell types in the vertebrate embryo. The intrinsic determinants that segregate neural crest cells from multipotential dorsal progenitors within the neural tube are poorly defined. In this
Critical to our understanding of the developmental potential of stem cells and subsequent control of their differentiation in vitro and in vivo is a thorough understanding of the genes that control stem cell fate. Here, we report that Foxd3, a
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