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Merck
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Documentos

A6500

Sigma-Aldrich

Acetylcholine bromide

≥99%

Sinónimos:

ACh

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About This Item

Fórmula lineal:
(CH3)3N(Br)CH2CH2OCOCH3
Número de CAS:
66-23-9
Peso molecular:
226.11
Beilstein/REAXYS Number:
3572117
EC Number:
200-622-4
MDL number:
MFCD00011814
UNSPSC Code:
51151519
PubChem Substance ID:
24891093
NACRES:
NA.25

assay

≥99%

form

powder

mp

140-143 °C (lit.)

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

[Br-].CC(=O)OCC[N+](C)(C)C

InChI

1S/C7H16NO2.BrH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1

InChI key

ZEHGKSPCAMLJDC-UHFFFAOYSA-M

Gene Information

human ... CHRM3(1131)

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Application

Acetylcholine is an endogenous neurotransmitter at cholinergic synapses that amplifies action potential of the sarcolemma thereby inducing muscle contractions. Acetylcholine bromide is used as an acetylcholine receptor agonist to identify, characterize and differentiate among types of cholinergic receptors. Acetylcholine bromide is used as an inhibitor to identify and characterize natural and mutated butyrylcholinesterase(s).

Biochem/physiol Actions

Endogenous neurotransmitter at cholinergic synapses; amplifies action potential of the sarcolemma thereby inducing muscle contractions.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Scott A Hollingsworth et al.
Nature communications, 10(1), 3289-3289 (2019-07-25)
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PloS one, 11(12), e0166291-e0166291 (2016-12-10)
Sickle cell disease patients display priapism that may progress to erectile dysfunction. However, little is known about the pathophysiological alterations of corpus cavernosum in sickle cell disease. Thus, this study aimed to evaluate the functional and molecular alterations of sympathetic
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Scientific reports, 7(1), 9938-9938 (2017-09-01)
Despite the mechanisms for endogenous nitroxyl (HNO) production and action being incompletely understood, pharmacological donors show broad therapeutic promise and are in clinical trials. Mass spectrometry and site-directed mutagenesis showed that chemically distinct HNO donors 1-nitrosocyclohexyl acetate or Angeli's salt
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Russell's viper (Daboia russelii) venom causes a range of clinical effects in humans. Hypotension is an uncommon but severe complication of Russell's viper envenoming. The mechanism(s) responsible for this effect are unclear. In this study, we examined the cardiovascular effects
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