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Merck
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A4284

Sigma-Aldrich

L-Asparragina monohydrate

suitable for cell culture, BioReagent

Sinónimos:

4-Amida del ácido(S)-2-aminosuccínico, 4-Amida del ácido L-aspártico, Ácido (S)-(+)-2-aminosuccinámico

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About This Item

Fórmula lineal:
NH2COCH2CH(NH2)COOH · H2O
Número de CAS:
5794-13-8
Peso molecular:
150.13
Beilstein/REAXYS Number:
1723527
EC Number:
200-735-9
MDL number:
MFCD00151038
UNSPSC Code:
12352209
PubChem Substance ID:
24890843
NACRES:
NA.75

biological source

synthetic

product line

BioReagent

assay

≥99% (TLC)

form

powder

technique(s)

cell culture | mammalian: suitable

color

white to off-white

mp

233-235 °C (lit.)

SMILES string

[H]O[H].N[C@@H](CC(N)=O)C(O)=O

InChI

1S/C4H8N2O3.H2O/c5-2(4(8)9)1-3(6)7;/h2H,1,5H2,(H2,6,7)(H,8,9);1H2/t2-;/m0./s1

InChI key

RBMGJIZCEWRQES-DKWTVANSSA-N

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Application

L-Asparagine monohydrate has been used:
  • as a media supplement to culture Black Mexican Sweet (BMS) cells
  • to prepare Adams III media to supplement C+Y medium for culturing Streptococcus pneumoniae
  • in an asparagine-rich diet to study the E0771 syngeneic breast tumor growth and survival in mice

Biochem/physiol Actions

L-Asparagine (L-Asp) is a nonessential amino acid involved in the synthesis of critical cellular proteins of human cells. It is synthesized from oxaloacetic acid. L-Asp is used as a growth supplement for tumor cells in in vitro conditions.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Asparagine anhydrous United States Pharmacopeia (USP) Reference Standard

USP

1043502

Asparagine anhydrous

Ácido L-aspártico

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A5474

Ácido L-aspártico

L-Glutamic acid from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%

Sigma-Aldrich

G8415

L-Glutamic acid

L-Prolina from non-animal source, meets EP, USP testing specifications, suitable for cell culture

Sigma-Aldrich

P5607

L-Prolina

L-Asparagine certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

51363

L-Asparagine

Suplemento GSEM 50 ×, liquid, sterile-filtered, suitable for cell culture

Sigma-Aldrich

G9785

Suplemento GSEM

Neurologic complications of chemotherapy and other newer and experimental approaches
Soffietti R, et al.
Handbook of Clinical Neurology, 1199-1218 null
Altered metabolism of leukemic cells: new therapeutic opportunity
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International Review of Cell and Molecular Biology, 336, 93-147 (2018)
Ana Romina Fox et al.
The New phytologist, 228(3), 973-988 (2021-01-08)
Plasma membrane (PM) intrinsic proteins (PIPs) are aquaporins facilitating the diffusion of water and small solutes. The functional importance of the PM organisation of PIPs in the interaction with other cellular structures is not completely understood. We performed a pull-down
Abigail S Krall et al.
Cell metabolism, 33(5), 1013-1026 (2021-02-21)
Mitochondrial respiration is critical for cell proliferation. In addition to producing ATP, respiration generates biosynthetic precursors, such as aspartate, an essential substrate for nucleotide synthesis. Here, we show that in addition to depleting intracellular aspartate, electron transport chain (ETC) inhibition
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Bio-protocol, 6(23) (2017-06-03)
Cell wall is a complex biopolymer on the surface of all Gram-positive bacteria. During infection, cell wall is recognized by the innate immune receptor Toll-like receptor 2 causing intense inflammation and tissue damage. In animal models, cell wall traffics from
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