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69453

Sigma-Aldrich

L-Homocysteine

≥98.0% (NT)

Sinónimos:

(S)-2-Amino-4-mercaptobutyric acid

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10 MG
MXP 1,919.00
50 MG
MXP 7,568.00

MXP 1,919.00

Disponible para envío el07 de abril de 2025Detalles

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10 MG
MXP 1,919.00
50 MG
MXP 7,568.00

About This Item

Fórmula lineal:
HSCH2CH2CH(NH2)COOH
Número de CAS:
6027-13-0
Peso molecular:
135.18
Número CE:
227-891-0
Número MDL:
MFCD00151320
Código UNSPSC:
12352204
ID de la sustancia en PubChem:
329761669
NACRES:
NA.32

MXP 1,919.00

Disponible para envío el07 de abril de 2025Detalles

Solicitar un pedido a granel

Nombre del producto

L-Homocysteine, ≥98.0% (NT)

Ensayo

≥98.0% (NT)

Formulario

powder

actividad óptica

[α]/D 25.5±1.5°, c = 1 in 1 M HCl

color

white

mp

263-265 °C

aplicaciones

cell analysis

enfermedades relevantes

Alzheimer′s disease

temp. de almacenamiento

−20°C

cadena SMILES

N[C@@H](CCS)C(O)=O

InChI

1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7)/t3-/m0/s1

Clave InChI

FFFHZYDWPBMWHY-VKHMYHEASA-N

Descripción general

L-homocysteine is used to diagnose homocystinuria.[1][2]

Aplicación

L-homocysteine has been used as a supplement in cell culture media.[1]

Acciones bioquímicas o fisiológicas

Elevated homocysteine levels in plasma and tissue are associated with brain atrophy in Alzheimer′s disease as well as in healthy eldery subjects. Increased homocysteine is due to deficiencies in vitamin B status, specifically folate, B6 and B12 vitamins, which act as cofactors for enzymes involved in homocysteine metabolism.

Envase

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Frases de peligro

H302

Clasificaciones de peligro

Acute Tox. 4 Oral

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
BCCM6820
BCCL8089
BCCJ9185
BCCH6167
BCCG9242

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K Mehlig et al.
Heart (British Cardiac Society), 99(23), 1761-1765 (2013-09-10)
An elevated level of total plasma homocysteine (tHcy) has been associated with risk of coronary heart disease (CHD). The level of tHcy is affected by lifestyle, in addition to genetic predisposition. The methylene tetrahydrofolate reductase (MTHFR) 677C>T polymorphism (rs1801133) is
James J H Chong et al.
Journal of the American Heart Association, 8(1), e011028-e011028 (2019-01-01)
Background Neutrophil gelatinase-associated lipocalin ( NGAL ) or lipocalin 2 may promote atherosclerosis and plaque instability leading to increased risk of cardiac events. We investigated the relationships between plasma NGAL , cardiovascular disease biomarkers, and long-term cardiac events. Methods and
Sanne Visser et al.
American journal of obstetrics and gynecology, 211(4), 373-373 (2014-03-19)
The aim of this study was to investigate which nonclassic cardiovascular biomarkers are associated with persistent endothelial dysfunction after pregnancy in women with a history of hypertensive pregnancy disorders compared with women with uncomplicated pregnancies. This was a systematic review
SAGE open medicine, 286054-286054 (2014)
Assessment of homocysteine status
Refsum H, et al.
Journal of inherited metabolic disease, 20(2), 286-294 (1997)
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Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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