39286

Hydroxystilbamidine bis(methanesulfonate)

suitable for fluorescence, ≥96.0% (HPLC)

• Sinónimos: 2-Hydroxystilbene-4,4′-dicarboxamidine bis(methanesulfonate), Fluoro-Gold
• Fórmula empírica (notación de Hill): C₁₈H₂₄N₄O₇S₂
• Número de CAS: 223769-64-0
• Peso molecular: 472.54
• Número MDL: MFCD01863083
• Código UNSPSC: 41116100
• ID de la sustancia en PubChem: 57649893
• NACRES: NA.32

Propiedades

• Ensayo: ≥96.0% (HPLC)
• Formulario: powder
• fluorescencia: λ_ex 318 nm; λ_em 560 nm in TBE Buffer
• idoneidad: suitable for fluorescence
• temp. de almacenamiento: 2-8°C
• cadena SMILES: CS(O)(=O)=O.CS(O)(=O)=O.NC(=N)c1ccc(cc1)\C=C\c2ccc(cc2O)C(N)=N
• InChI: 1S/C16H16N4O.2CH4O3S/c17-15(18)12-5-2-10(3-6-12)1-4-11-7-8-13(16(19)20)9-14(11)21;2*1-5(2,3)4/h1-9,21H,(H3,17,18)(H3,19,20);2*1H3,(H,2,3,4)/b4-1+;;
• Clave InChI: YGNSQKCULHSJDC-HFPMQDOPSA-N

Descripción

Descripción general

Hydroxystilbamidine bis (methanesulfonate), also known as Fluoro-Gold, is a retrograde fluorescent tracer. Chemically, Hydroxystilbamidine is a weak base and can cross cell membranes in its uncharged form.[1]

A few properties of Hydroxystilbamidine bis (methanesulfonate) are:[2]

• Intense Fluorescence.
• Extensive filling of dendrites.
• High Resistance to fading.
• No uptake by undamaged fibers.
• No diffusion from labelled cells.
• Highly compatible with other neuro-histochemical techniques.

Aplicación

Hydroxystilbamidine bis(methanesulfonate), a fluorescent retrograde tracer (axonal transport), is used for neural mapping in microanatomical research.

Hydroxystilbamidine bis (methanesulfonate) or Fluoro-Gold (FG) is used to label neurons and investigate the early effects of hearing loss.[3] It is used to study morphological features of extensive axonal projections within the CNS by labelling the cells.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H315,H319,H335
• Consejos de prudencia: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Clasificaciones de peligro: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órganos de actuación: Respiratory system
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves