30320

Cytidine 5′-triphosphate disodium salt hydrate

≥90.0% (HPLC)

• Sinónimos: 5-CTP-Na₂, CTP
• Fórmula empírica (notación de Hill): C₉H₁₄N₃Na₂O₁₄P₃ · xH₂O
• Número de CAS: 652154-13-7
• Peso molecular: 527.12 (anhydrous basis)
• Beilstein: 3582735
• Número MDL: MFCD00150809
• Código UNSPSC: 41106305
• ID de la sustancia en PubChem: 57648425
• NACRES: NA.51

Propiedades

• Ensayo: ≥90.0% (HPLC)
• Formulario: solid
• impurezas: ≤12% water
• solubilidad: H₂O: 50 mg/mL, clear, colorless
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• cadena SMILES: O.[Na+].[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O
• InChI: 1S/C9H16N3O14P3.2Na.H2O/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18);;;1H2/q;2*+1;/p-2/t4-,6-,7-,8-;;;/m1.../s1
• Clave InChI: IJMSOWKYYIROGP-LLWADOMFSA-L

Descripción

Aplicación

Cytidine 5′-triphosphate disodium salt hydrate has been used:

• in the oligonucleotide synthesis for silver nanoclusters interaction studies[1]
• as an anion source for fluorescence emission and titration curve-analysis of hypocrellin A-zinc(II) complex[2]
• in fluorescence emission experiments of copper(II)–2,6-bis(2-benzimidazolyl)pyridine complex[3]

Cytidine 5γ-triphosphate (CTP) is used to synthesize RNA by various RNA polymerases. Cytidine 5γ-triphosphate (CTP) is a substrate for CMP-neuNAc synthetase(s) which produce CMP-neuNAc used in sialylation reactions. As a substrate of CTP:phosphocholine cytidylyltransferase(s) (CT), CTP supports the formation of phosphatidylcholine via the formation of CDP-choline.

Acciones bioquímicas o fisiológicas

Cytidine 5′-triphosphate (CTP) is essential for the synthesis of DNA and is a mediator of many physiological processes in living systems. It is crucial for the dolichol phosphorylation, cholesterol transport and is involved in the allosteric regulation of aspartate transcarbamylase. It is also used in the treatment of disease related brain.[4]

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): 235.4 °F - closed cup
• Punto de inflamabilidad (°C): 113 °C - closed cup
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)