Saltar al contenido
Merck
Todas las fotos(2)

Documentos

22244

Sigma-Aldrich

Ceramide from bovine spinal cord

≥98.0% (TLC)

Sinónimos:

Bovine Spinal Cord Ceramide

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(2)

About This Item

MDL number:
MFCD00146359
UNSPSC Code:
12352211
NACRES:
NA.25

biological source

bovine spinal cord

assay

≥98.0% (TLC)

form

solid

impurities

α-hydroxy fatty acids

solubility

chloroform/methanol (99:1): 20 mg/mL, clear, colorless

lipid type

sphingolipids

shipped in

wet ice

storage temp.

−20°C

¿Está buscando productos similares? Visita Guía de comparación de productos

Application

Ceramide is used to investigate effects on programmed cell death (apoptosis) and insulin signaling.

Biochem/physiol Actions

Ceramide is a minor component of cell membranes. Activates atypical protein kinase C (e.g., PKCzeta) .

Preparation Note

from cerebrosides by a modification of the procedure by H.E. Carter et al., J. Lipid Res. 2, 228 (1961)

Other Notes

Sales restrictions may apply

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Darren J Powell et al.
Molecular and cellular biology, 23(21), 7794-7808 (2003-10-16)
Ceramide is generated in response to numerous stress-inducing stimuli and has been implicated in the regulation of diverse cellular responses, including cell death, differentiation, and insulin sensitivity. Recent evidence indicates that ceramide may regulate these responses by inhibiting the stimulus-mediated
M G Yefimova et al.
Human reproduction (Oxford, England), 35(6), 1346-1362 (2020-06-13)
Do human granulosa cells (GCs) ingest and destroy apoptotic oocytes? Somatic GCs ingest and destroy apoptotic oocytes and other apoptotic substrates through unconventional autophagy-assisted phagocytosis. Most (99%) ovarian germ cells undergo apoptosis through follicular atresia. The mode of cleaning of
Huijing Yin et al.
Nature communications, 12(1), 4230-4230 (2021-07-11)
Extracellular matrix protein-1 (ECM1) promotes tumorigenesis in multiple organs but the mechanisms associated to ECM1 isoform subtypes have yet to be clarified. We report in this study that the secretory ECM1a isoform induces tumorigenesis through the GPR motif binding to
Marta Pera et al.
The EMBO journal, 36(22), 3356-3371 (2017-10-12)
In the amyloidogenic pathway associated with Alzheimer disease (AD), the amyloid precursor protein (APP) is cleaved by β-secretase to generate a 99-aa C-terminal fragment (C99) that is then cleaved by γ-secretase to generate the β-amyloid (Aβ) found in senile plaques.

Artículos

Mitochondrial Stress and ROS

Cellular oxidative stress is countered by enzymatic scavengers and antioxidant modulators against reactive oxygen species damage.

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico