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Sigma-Aldrich

9-Oxo-10(9H)-acridineacetic acid

for HPLC derivatization, ≥99.0% (T)

Sinónimos:

(9,10-Dihydro-9-oxo-10-acridinyl)acetic acid, 10-(Carboxymethyl)-9(10H)acridone

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About This Item

Fórmula empírica (notación de Hill):
C15H11NO3
Número de CAS:
38609-97-1
Peso molecular:
253.25
Beilstein/REAXYS Number:
227508
MDL number:
MFCD00157050
UNSPSC Code:
12352106
PubChem Substance ID:
329751585
NACRES:
NA.32

grade

for HPLC derivatization

assay

≥99.0% (T)

form

solid

mp

~289 °C (dec.)

SMILES string

OC(=O)CN1c2ccccc2C(=O)c3ccccc13

InChI

1S/C15H11NO3/c17-14(18)9-16-12-7-3-1-5-10(12)15(19)11-6-2-4-8-13(11)16/h1-8H,9H2,(H,17,18)

InChI key

UOMKBIIXHQIERR-UHFFFAOYSA-N

Application

9-Oxo-10(9H)-acridineacetic acid and its analogs are used to study their potential activity as interferon inducers.

Other Notes

Reagent for pre-column derivatization of amino acids for fluorescent determination in HPLC; Building block in pharmaceutics

Recommended products

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Competition of sodium salt of 9-oxo-10-acridineacetic acid with analogs during induction of interferon in the mouse bone marrow-derived macrophages.
Szulc B, Inglot AD, Szulc Z, Mlochowski J.
Arch. Immunol. Ther. Exp., 33, 287-297 (1985)
E D Bazhanova
Eksperimental'naia i klinicheskaia farmakologiia, 75(10), 42-46 (2012-12-18)
A detailed analysis of the literature data gives contradictory information about the role of interferon-alpha in the regulation of apoptosis, while there are almost no data on the participation of cycloferon in this process. Results of original experiments in recent
S.A. Lyakhov et al.
Pharmazie, 49, 367-367 (1994)
A V Gordeets et al.
Eksperimental'naia i klinicheskaia farmakologiia, 76(2), 17-19 (2013-05-02)
The case records of 120 children older than 4 years with rotavirus infection have been studied. In this group, 22 patients received basic therapy and 98 received complex therapy with cycloferon. Appropriate therapy resulted in rapid positive dynamics of clinical
V M Frolov et al.
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 57(5-6), 18-27 (2012-11-20)
The use of reamberin and cycloferon combination for increasing the antibacterial therapy efficacy in patients with chronic sepsis (CS) was studied. It was shown that the combination provided more rapid elimination of the CS exacerbation symptoms, normalization of the hematologic
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