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Merck

S2155000

Sulfasalazine

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

2-Hydroxy-5-{{4-[(2-pyridinylamino)sulfonyl]phenyl}azo}benzoic acid, 5-[4-(2-Pyridylsulfamoyl)phenylazo]salicylic acid, Salicylazosulfapyridine

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About This Item

Fórmula empírica (notación de Hill):
C18H14N4O5S
Número de CAS:
Peso molecular:
398.39
Beilstein:
356241
Número MDL:
Código UNSPSC:
41116107
ID de la sustancia en PubChem:

familia API

sulfasalazine

mp

260-265 °C (dec.) (lit.)

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

OC(=O)c1cc(ccc1O)\N=N\c2ccc(cc2)S(=O)(=O)Nc3ccccn3

InChI

1S/C18H14N4O5S/c23-16-9-6-13(11-15(16)18(24)25)21-20-12-4-7-14(8-5-12)28(26,27)22-17-3-1-2-10-19-17/h1-11,23H,(H,19,22)(H,24,25)/b21-20+

Clave InChI

NCEXYHBECQHGNR-QZQOTICOSA-N

Información sobre el gen

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Sulfasalazine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Pictogramas

Health hazardEnvironment

Palabra de señalización

Danger

Frases de peligro

Clasificaciones de peligro

Aquatic Chronic 2 - Carc. 2 - Repr. 2 - Resp. Sens. 1 - Skin Sens. 1

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 2


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Miscellaneous treatments, I: sulfasalazine and pentoxifylline: unapproved uses, dosages, or indications.
Ronni Wolf et al.
Clinics in dermatology, 20(5), 531-546 (2002-11-19)
Nail lesions in psoriatic arthritis: recovery with sulfasalazine treatment.
J C Gerster et al.
Annals of the rheumatic diseases, 61(3), 277-277 (2002-02-07)
Greg L Plosker et al.
Drugs, 65(13), 1825-1849 (2005-08-24)
Sulfasalazine (salazosulfapyridine) [Azulfidine, Salazopyrin] is a well established disease-modifying antirheumatic drug (DMARD) used in the treatment of patients with rheumatoid arthritis. Clinical trials with sulfasalazine have used an array of measures of disease activity, such as the number of tender
Fabrice Michel et al.
Joint, bone, spine : revue du rhumatisme, 72(1), 82-85 (2005-02-01)
DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) is a drug-induced hypersensitivity syndrome that can mimic malignant lymphoma. We report a case in a 63-year-old woman who had been on sulfasalazine for 2 months to treat rheumatoid arthritis. She was
Victoria Linares et al.
Expert opinion on drug safety, 10(2), 253-263 (2011-01-12)
Sulfasalazine (SASP) is a drug commonly used in the treatment of inflammatory bowel diseases (IBD) such as ulcerative colitis and Crohn's disease (CD) and rheumatoid arthritis (RA). A high incidence of side effects limits therapy with this drug. Getting a

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