PHL82530

(−)-Englerin A

phyproof^® Reference Substance

• Fórmula empírica (notación de Hill): C₂₆H₃₄O₆
• Número de CAS: 1094250-15-3
• Peso molecular: 442.54
• UNSPSC Code: 41116107
• NACRES: NA.24

Propiedades

• grade: primary reference standard
• product line: phyproof^® Reference Substance
• assay: ≥95.0% (HPLC)
• manufacturer/tradename: PhytoLab
• application(s): food and beverages
• format: neat

Descripción

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Application

• Englerin A as a Potent Selective Inhibitor of Renal Cancer: Englerin A has demonstrated remarkable efficacy in inducing cytotoxicity in renal cancer cells through the hyperphosphorylation of Hsp27 and as a promising antitumor agent in cancer pharmacotherapy (Neo et al., 2022).


• Natural Product TRPC4 Activator: Englerin A′s role in inhibiting T-type voltage-gated calcium channels showcases its unique mechanism of action as a natural product activator of TRPC4/TRPC5 ion channels, offering new avenues for therapeutic interventions in cancer biology (Wardas et al., 2023).

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable