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Documentos clave

O0146010

Olsalazine sodium for performance test

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

4,4′-Dihydroxyazobenzene-3,3′-dicarboxylic acid disodium salt, 5,5′-Azobis(salicylic acid, sodium salt), Mordant Yellow 5

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About This Item

Fórmula empírica (notación de Hill):
C14H8N2Na2O6
Número de CAS:
6054-98-4
Peso molecular:
346.20
Código UNSPSC:
41116107
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

olsalazine

fabricante / nombre comercial

EDQM

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

[Na+].[Na+].N(\N=C2/C=C(C(=O)C=C/2)C(=O)[O-])c1cc(c(cc1)O)C(=O)[O-]

InChI

1S/C14H10N2O6.2Na/c17-11-3-1-7(5-9(11)13(19)20)15-16-8-2-4-12(18)10(6-8)14(21)22;;/h1-6,15,17H,(H,19,20)(H,21,22);;/q;2*+1/p-2/b16-8-;;

Clave InChI

QQWFSVYVHLECFP-XBPUGJBTSA-L

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Olsalazine sodium for performance test EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Producto relacionado

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Lot/Batch Number

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Florian Loher et al.
The Journal of pharmacology and experimental therapeutics, 305(2), 549-556 (2003-02-28)
Mesopram, a specific inhibitor of type-4 phosphodiesterase, decreases the synthesis of tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma). In the present study, we investigated the effect of mesopram in dextran sulfate sodium (DSS)-induced murine colitis. In the preventive model, colitis
Gerassimos J Mantzaris et al.
The American journal of gastroenterology, 99(6), 1122-1128 (2004-06-08)
The aim of this prospective study was to assess whether the coadministration of azathioprine (AZA) and olsalazine is superior to AZA monotherapy in maintaining remission of steroid-dependent ulcerative colitis (UC). Patients with steroid-dependent UC in remission were randomized to receive
Laurie M Edmond et al.
Inflammatory bowel diseases, 9(1), 10-17 (2003-03-27)
The toxic, bacterial metabolite sulfide is implicated in ulcerative colitis. Ulcerative colitis patients taking 5-aminosalicylic acid-containing drugs have lower fecal sulfide levels than those not taking these drugs. The effects of sulfasalazine, balsalazide, olsalazine, and 5-aminosalicylic acid on sulfide production
M V Singer et al.
Hepato-gastroenterology, 53(69), 317-321 (2006-06-27)
In the treatment of ulcerative colitis, 5-aminosalicylic acid is the standard therapy for both acute exacerbations of the disease and the maintenance of remission. Clinical studies have shown that olsalazine (Dipentum)--a prodrug converted to two molecules of 5-ASA by colonic
When less is not more but at least equivalent.
Stephen Holland
Inflammatory bowel diseases, 10(6), 890-891 (2005-01-01)
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