BP715

Cocaine hydrochloride

British Pharmacopoeia (BP) Reference Standard

• Sinónimos: Ecgonine methyl ester benzoate hydrochloride
• Fórmula empírica (notación de Hill): C₁₇H₂₁NO₄ · HCl
• Número de CAS: 53-21-4
• Peso molecular: 339.81
• MDL number: MFCD00058119
• UNSPSC Code: 41116107
• NACRES: NA.24

Propiedades

• grade: pharmaceutical primary standard
• API family: cocaine
• form: solid
• shelf life: limited shelf life, expiry date on the label
• manufacturer/tradename: BP
• drug control: estupefaciente (Spain); Decreto Lei 15/93: Tabela IB (Portugal)
• application(s): pharmaceutical; pharmaceutical (small molecule); pharmaceutical small molecule
• format: neat
• storage temp.: 2-8°C
• SMILES string: Cl.COC(=O)[C@H]1[C@H](C[C@@H]2CC[C@H]1N2C)OC(=O)c3ccccc3
• InChI: 1S/C17H21NO4.ClH/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11;/h3-7,12-15H,8-10H2,1-2H3;1H/t12-,13+,14-,15+;/m0./s1
• InChI key: PIQVDUKEQYOJNR-VZXSFKIWSA-N

Descripción

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Cocaine hydrochloride BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Adrenaline and Cocaine Intranasal Solution / Epinephrine and Cocaine Intranasal Solution

Cocaine Paste

Cocaine Eye Drops

Biochem/physiol Actions

Inhibits the dopamine, norepinephrine, and serotonin transporters with K_is of about 300 nM, 900 nM, and 400 nM, respectively. Unlike amphetamines, it has no effect on catecholamine release.

Packaging

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Other Notes

Sales restrictions may apply.

Información de seguridad

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H300 + H330,H336,H361d
• pcodes: P202 - P260 - P264 - P271 - P280 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Repr. 2 - STOT SE 3
• target_organs: Central nervous system
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable