45661

Strychnine

PESTANAL^®, analytical standard

• Sinónimos: (−)-Strychnine
• Fórmula empírica (notación de Hill): C₂₁H₂₂N₂O₂
• Número de CAS: 57-24-9
• Peso molecular: 334.41
• Beilstein/REAXYS Number: 52979
• EC Number: 200-319-7
• MDL number: MFCD00005941
• UNSPSC Code: 41116107
• PubChem Substance ID: 329756875

Propiedades

• grade: analytical standard
• Quality Level: 100
• product line: PESTANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• mp: 284-286 °C (lit.)
• application(s): agriculture; cleaning products; cosmetics; environmental; food and beverages; forensics and toxicology; personal care; pharmaceutical (small molecule)
• format: neat
• SMILES string: [H][C@@]12CC(=O)N3c4ccccc4[C@]56CC[N@H]7CC(=CCO1)[C@]([H])(C[C@@H]57)[C@]2([H])[C@]36[H]
• InChI: 1S/C21H22N2O2/c24-18-10-16-19-13-9-17-21(6-7-22(17)11-12(13)5-8-25-16)14-3-1-2-4-15(14)23(18)20(19)21/h1-5,13,16-17,19-20H,6-11H2/t13-,16-,17-,19-,20-,21+/m0/s1
• InChI key: QMGVPVSNSZLJIA-FVWCLLPLSA-N

Descripción

General description

Strychnine is an alkaloid, available as a bioactive component in Semen Strychni, exhibiting analgesic, anti-inflammatory and anti-tumor effects. It is widely used in neurological research, treatment of genetic disorder nonketotic hyperglycinemia, treatment of stomach ailments, etc.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Strychnine may be used as an analytical reference standard for the quantification of the analyte in biological samples using liquid chromatography coupled to electrospray ionization mass spectrometry.

Biochem/physiol Actions

Produce convulsiones; antagonista en los receptores de glicina no competitivo con el receptor NMDA.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictograms: GHS06,GHS09
• signalword: Danger
• hcodes: H300 + H310,H410
• pcodes: P262 - P264 - P273 - P280 - P301 + P310 - P302 + P352 + P310
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 2
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges