37018

Tenuazonic acid

analytical standard

• Sinónimos: (5S)-3-Acetyl-1,5-dihydro-4-hydroxy-5-[(1S)-1-methylpropyl]-2H-pyrrol-2-one, (S)-3-Acetyl-5-(S)-sec-butyltetramic acid, (S)-3-Acetyl-5-sec-butyl-4-hydroxy-3-pyrrolin-2-one
• Fórmula empírica (notación de Hill): C₁₀H₁₅NO₃
• Número de CAS: 610-88-8
• Peso molecular: 197.23
• Beilstein/REAXYS Number: 3589518
• MDL number: MFCD00242648
• UNSPSC Code: 85151701
• PubChem Substance ID: 329755583
• NACRES: NA.24

Propiedades

• grade: analytical standard
• Quality Level: 100
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): cleaning products; cosmetics; food and beverages; personal care
• format: neat
• storage temp.: −20°C
• SMILES string: CC[C@H](C)[C@@H]1NC(=O)C(C(C)=O)=C1O
• InChI: 1S/C10H15NO3/c1-4-5(2)8-9(13)7(6(3)12)10(14)11-8/h5,8,13H,4H2,1-3H3,(H,11,14)/t5-,8-/m0/s1
• InChI key: CEIZFXOZIQNICU-XNCJUZBTSA-N

Descripción

General description

Tenuazonic acid is a biologically active compound and its mode of action involves the inhibition of protein biosynthesis.[1]

Tenuazonic acid is a mycotoxin, which belongs to the class of tetramic acids, the largest family of natural products.[2] It is generally isolated from phytopathogenic fungal species like Alternaria alternata, A. longipes and A. tenuissima.[2]

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Tenuazonic acid may be used as an analytical reference standard for the quantification of the analyte in the following:

• Cornflakes using high-performance liquid chromatography (HPLC) technique.[3]
• Human urine samples using isotope dilution assay method and liquid chromatography coupled to a hybrid triple quadrupole/linear ion trap mass spectrometer.[4]
• Cereals using high-performance liquid chromatography–electrospray ionization ion-trap multistage mass spectrometry (HPLC- ESI ion-trap (IT) MS²). ESI Fourier transform-ion cyclotron resonance tandem mass spectrometry (FTICR-MS²) technique is used for product characterization, post derivatization with 2,4-dinitrophenylhydrazine.[1]

Reconstitution

Dried down, ~100 μg/mL after reconstitution with 1 mL of water

Analysis Note

purity : ≥96.0% (HPLC)

Información de seguridad

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable