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Flubendazol

VETRANAL®, analytical standard

Sinónimos:

Flumoxanal, Methyl [5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate

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100 MG
MXP 4,616.00

MXP 4,616.00

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100 MG
MXP 4,616.00

About This Item

Fórmula empírica (notación de Hill):
C16H12FN3O3
Número de CAS:
31430-15-6
Peso molecular:
313.28
Número CE:
250-624-4
Número MDL:
MFCD00871999
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329754807
NACRES:
NA.24

MXP 4,616.00

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grado

analytical standard

Nivel de calidad

100

Línea del producto

VETRANAL®

caducidad

limited shelf life, expiry date on the label

técnicas

HPLC: suitable
gas chromatography (GC): suitable

aplicaciones

forensics and toxicology
pharmaceutical (small molecule)

Formato

neat

cadena SMILES

COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3ccc(F)cc3

InChI

1S/C16H12FN3O3/c1-23-16(22)20-15-18-12-7-4-10(8-13(12)19-15)14(21)9-2-5-11(17)6-3-9/h2-8H,1H3,(H2,18,19,20,22)

Clave InChI

CPEUVMUXAHMANV-UHFFFAOYSA-N

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Descripción general

Flubendazol is a broad spectrum anthelmintic, which belongs to the class of compounds known as benzimidazoles.[1][2] It can be widely used in veterinary and human medicine.[3] It mainly finds applications in deworming poultry[1][2], swine[1][2], dogs and cats.[2]
Flubendazol is an injectable benzimidazole drug; though it is poorly absorbed it is quite effective in the treatment of trycocephalus, ascaris and oxyuriasis in both children and adults.[4]

Aplicación

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
VETRANAL® analytical standard can be used in the liquid chromatography coupled to mass spectrometry (LC-MS/MS) procedure, performed for the analysis of macrocyclic lactones in milk.[5]

Información legal

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 2

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
BCCM4882
BCCD3951
BCBW0774

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Gabriel Rübensam et al.
Analytica chimica acta, 705(1-2), 24-29 (2011-10-04)
In this work a method is proposed and demonstrated for the analysis of the macrocyclic lactones abamectin, doramectin, eprinomectin, ivermectin and moxidectin in bovine milk by liquid chromatography coupled to mass spectrometry (LC-MS/MS) and liquid chromatography with fluorescence detection (LC-FL).
Paul A Spagnuolo et al.
Blood, 115(23), 4824-4833 (2010-03-30)
On-patent and off-patent drugs with previously unrecognized anticancer activity could be rapidly repurposed for this new indication given their prior toxicity testing. To identify such compounds, we conducted chemical screens and identified the antihelmintic flubendazole. Flubendazole induced cell death in
H Bártíková et al.
Journal of veterinary pharmacology and therapeutics, 33(1), 56-62 (2010-05-07)
The aim of this project was to study the influence of haemonchosis, a common parasitic infection of small ruminants caused by Haemonchus contortus, on the activity of biotransformation enzymes and on in vitro flubendazole (FLU) biotransformation in liver and small
V Krízová et al.
Journal of veterinary pharmacology and therapeutics, 32(6), 606-612 (2010-05-07)
Flubendazole (FLU) is indicated for control of helminthoses in pig and avian species (monogastric animals) and its corresponding pharmacokinetics are well known. The information on FLU's pharmacokinetic behavior in animal species with forestomach (ruminants) has been limited although the use
Laura Ceballos et al.
Chemotherapy, 56(5), 386-392 (2010-10-16)
Cystic echinococcosis (CE) is an important public health problem worldwide. Flubendazole, administered in tablets, has shown poor in vivo efficacy against CE in humans. However, flubendazole prepared as a solution caused a marked reduction in hydatid cysts developed in mice.
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