03557
Poli(etilenglicol)
tested according to Ph. Eur., 35,000
Sinónimos:
PEG
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About This Item
Fórmula lineal:
H(OCH2CH2)nOH
Número de CAS:
Número MDL:
Código UNSPSC:
12161900
ID de la sustancia en PubChem:
NACRES:
NA.21
Productos recomendados
Agency
tested according to Ph. Eur.
Nivel de calidad
Formulario
powder
mol peso
~35000
solubilidad
aliphatic hydrocarbons: slightly soluble
organic solvents: soluble
aplicaciones
pharmaceutical (small molecule)
cadena SMILES
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
Clave InChI
LYCAIKOWRPUZTN-UHFFFAOYSA-N
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Aplicación
Poly (ethylene glycol) can be used as a test compound utilized in the overproduction and purification of recombinant Lactobacillus reuteri LrNDT.[1] It can also be used for concentrating the mutants with lower secretion levels used in ELISAs for the quantitation of shgp190 and of the LIF/shgp190 complexes.[2]
Acciones bioquímicas o fisiológicas
Nota de preparación
Poly(ethylene glycol) dissolves in many organic solvents and is readily soluble in aromatic hydrocarbons. It also slightly dissolves in aliphatic hydrocarbons.
Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
WGK 1
Punto de inflamabilidad (°F)
281.5 °F - closed cup
Punto de inflamabilidad (°C)
138.6 °C - closed cup
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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Jesús Fernández-Lucas et al.
Applied and environmental microbiology, 76(5), 1462-1470 (2010-01-06)
A novel type II nucleoside 2'-deoxyribosyltransferase from Lactobacillus reuteri (LrNDT) has been cloned and overexpressed in Escherichia coli. The recombinant LrNDT has been structural and functionally characterized. Sedimentation equilibrium analysis revealed a homohexameric molecule of 114 kDa. Circular dichroism studies
Juliette Bitard et al.
The Journal of biological chemistry, 278(18), 16253-16261 (2003-02-26)
The leukemia inhibitory factor (LIF) receptor comprises the low affinity binding chain gp190 and the high affinity converter gp130. The ectodomain of gp190 is among the most complex in the hematopoietin receptor family, because it contains two typical cytokine receptor
J L Cleland et al.
The Journal of biological chemistry, 267(19), 13327-13334 (1992-07-05)
Polyethylene glycol (PEG) inhibited aggregation during refolding of bovine carbonic anhydrase B (CAB) through the formation of a nonassociating PEG-intermediate complex. Stoichiometric concentrations of PEG were required for complete recovery of active protein during refolding at aggregating conditions. For example
J L Cleland et al.
Bio/technology (Nature Publishing Company), 10(9), 1013-1019 (1992-09-01)
Previous studies on the refolding of recombinant bovine carbonic anhydrase B (CAB) indicated that polyethylene glycol (PEG) significantly enhanced the recovery of active protein by reducing aggregation. To further test the ability of PEG to enhance refolding, three recombinant human
Mark A Rice et al.
Acta biomaterialia, 5(1), 152-161 (2008-09-17)
Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide
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