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01580590

Ginsenoside Rf

primary reference standard

Sinónimos:

(3β,6α,12β)-3,12,20-Trihydroxydammar-24-en-6-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside

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10 MG
MXP 15,199.00

MXP 15,199.00

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10 MG
MXP 15,199.00

About This Item

Fórmula empírica (notación de Hill):
C42H72O14
Número de CAS:
52286-58-5
Peso molecular:
801.01
Número MDL:
MFCD00210509
Código UNSPSC:
85151701
ID de la sustancia en PubChem:
329747330
NACRES:
NA.24

MXP 15,199.00

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grado

primary reference standard

caducidad

limited shelf life, expiry date on the label

fabricante / nombre comercial

HWI

aplicaciones

food and beverages

temp. de almacenamiento

−20°C

cadena SMILES

[H][C@]1(O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@@]2([H])O[C@H]3C[C@]4(C)[C@]([H])(C[C@@H](O)[C@]5([H])[C@]([H])(CC[C@@]45C)[C@@](C)(O)CC\C=C(/C)C)[C@@]6(C)CC[C@H](O)C(C)(C)[C@]36[H]

InChI

1S/C42H72O14/c1-20(2)10-9-13-42(8,52)21-11-15-40(6)28(21)22(45)16-26-39(5)14-12-27(46)38(3,4)35(39)23(17-41(26,40)7)53-37-34(32(50)30(48)25(19-44)55-37)56-36-33(51)31(49)29(47)24(18-43)54-36/h10,21-37,43-52H,9,11-19H2,1-8H3/t21-,22+,23-,24+,25+,26+,27-,28-,29+,30+,31-,32-,33+,34+,35-,36-,37+,39+,40+,41+,42-/m0/s1

Clave InChI

UZIOUZHBUYLDHW-XUBRWZAZSA-N

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Descripción general

Ginsenoside is a steroid-like molecular component having gonane steroid nucleus along with different sugar moieties attached to them found in the roots of Panax ginseng.[1] Ginsenoside Rf, a variety of ginseng saponins with attached sugars moieties which inhibits the Ca2+ channels present in primary sensory neurons.[2]
Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Aplicación

It may be used as reference standard in HPLC-MS/MS analysis of human plasma to determine Ginsenosides from herbal products containing Panax ginseng and Panax quinquefolius.[3]

Otras notas

This compound is commonly found in plants of the genus: panax

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Frases de peligro

H302

Clasificaciones de peligro

Acute Tox. 4 Oral

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
HWI02364
HWI01522-2
HWI01522-1

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Noel S Quiming et al.
Analytical and bioanalytical chemistry, 389(5), 1477-1488 (2007-09-07)
The influences of the organic component of the mobile phase and the column temperature on the retention of ginsenosides on a poly(vinyl alcohol) (PVA) bonded stationary phase operated under hydrophilic interaction chromatographic mode were investigated. The retention of the ginsenosides
The antimetastatic and immunomodulating activities of ginseng minor glycosides.
A M Popov et al.
Doklady. Biochemistry and biophysics, 380, 309-312 (2001-12-01)
Sunoh Kim et al.
Biochemical and biophysical research communications, 365(3), 399-405 (2007-11-21)
In the present study, we have examined any possible involvement of L-type Ca(2+) channels in ginseng-mediated neuroprotective actions. Exposure to a 50mM KCl (high-K) produced neuronal cell death, which was blocked by a selective L-type Ca(2+) channel blocker in cultured
Cuk-seong Kim et al.
Acta pharmacologica Sinica, 26(5), 551-558 (2005-04-22)
To examine the effects of ginseng saponins on the heterologously expressed human ether-a-go-go related gene (HERG) that encodes the rapid component of the delayed rectifier K+ channel. A two-electrode voltage clamp technique was used. HERG currents were recorded in Xenopus
J J Nah et al.
Biological & pharmaceutical bulletin, 23(5), 523-526 (2000-05-24)
A rapid and sensitive indirect competitive enzyme immunoassay method has been developed for quantitating ginsenoside Rf (Rf) in crude total Panax ginseng saponins and in rat plasma using high titer mouse monoclonal antibody (mAb) raised against a conjugate of Rf
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Optimize HPLC method for ginsenoside separation using a mixture, applying it to American Ginseng root, with conditions and chromatograms shown.

High-Performance Thin-Layer Chromatography: A Fast and Efficient Fingerprint Analysis Method for Medicinal Plants

In this article we present several HPTLC applications and analytical standards for ginsenosides.

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