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Merck

24-1450

Sigma-Aldrich

Phenolphthalein

SAJ first grade, ≥97.0%

Sinónimos:

3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone

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About This Item

Fórmula empírica (notación de Hill):
C20H14O4
Número de CAS:
Peso molecular:
318.32
Colour Index Number:
764
Beilstein/REAXYS Number:
284423
EC Number:
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:

grade

SAJ first grade

assay

≥97.0%

form

solid

availability

available only in Japan

mp

261-263 °C (lit.)

solubility

acetone: soluble

SMILES string

Oc1ccc(cc1)C2(OC(=O)c3ccccc23)c4ccc(O)cc4

InChI

1S/C20H14O4/c21-15-9-5-13(6-10-15)20(14-7-11-16(22)12-8-14)18-4-2-1-3-17(18)19(23)24-20/h1-12,21-22H

InChI key

KJFMBFZCATUALV-UHFFFAOYSA-N

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pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Carc. 1B - Muta. 2 - Repr. 2 - Skin Irrit. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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To identify specific bacterial thymidylate synthase (TS) inhibitors, we exploited phenolphthalein (PTH), which inhibits both bacterial and human enzymes. The X-ray crystal structure of Lactobacillus casei TS (LcTS) that binds PTH showed multiple binding modes of the inhibitor, which prevented

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