MABF116

Anti-CD3 gamma delta (HMT3-2) Antibody, clone Ham25-1157

clone Ham25-1157, from hamster

• Sinónimos: T-cell surface glycoprotein CD3 gamma chain, T-cell receptor T3 gamma chain, CD3g, HMT3-2
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• biological source: hamster
• antibody form: purified antibody
• antibody product type: primary antibodies
• clone: Ham25-1157, monoclonal
• species reactivity: human
• species reactivity (predicted by homology): mouse (based on 100% sequence homology)
• technique(s): flow cytometry: suitable
• NCBI accession no.: NP_033980
• UniProt accession no.: P11942
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... CD3G(917)

Descripción

General description

The CD3 complex is composed of six polypeptides with usually four different transmembrane CD3 chains: gamma, delta, epsilon and zeta. CD3 is first detectable in early thymocytes and one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, during early stages of maturation, the CD3 antigen is predominantly present in the cell cytoplasm. In medullary thymocytes, it is detected on the cell surface. The majority of T cell neoplasms also expresses CD3, but it is absent from non-T-cell lymphoid malignancies.

Specificity

This antibody recognizes CD3 gamma delta.

Immunogen

Purified protein corresponding to mouse CD3 gamma delta.

Application

Anti-CD3 gamma delta (HMT3-2) Antibody, clone Ham25-1157 detects level of CD3 gamma delta (HMT3-2) & has been published & validated for use in FC.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Quality

Evaluated by Flow Cytometry in Jurkat cells.

Flow Cytometry Analysis: 2.5 µg/mL of this antibody detected CD3 gamma delta in 1X10E5 Jurkat cells.

Target description

21 kDa calculated

Physical form

Format: Purified

Protein G Purified

Purified armenian hamster monoclonal IgG2bλ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Jurkat cells

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable