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FCMAB257P

Sigma-Aldrich

Milli-Mark®Anti-Glial Fibrillary Acidic Protein-PE Antibody, clone GA5

clone GA5, Milli-Mark®, from mouse

Sinónimos:

GFAP

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

conjugate

PE

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

GA5, monoclonal

species reactivity

human

manufacturer/tradename

Milli-Mark®

technique(s)

flow cytometry: suitable

isotype

IgG1κ

NCBI accession no.

NP_002046

UniProt accession no.

P14136

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... GFAP(2670)

Categorías relacionadas

General description

Glial fibrillary acidic protein is a class-III intermediate filament. GFAP is the main constituent of intermediate filaments in astrocytes and serves as a cell specific marker that distinguishes differentiated astrocytes from other glial cells during the development of the central nervous system.

Specificity

Antibody recognizes Human Glial Fibrillary Acidic Protein.

Immunogen

Purified glial filament (Debus, E., 1983).

Application

Milli-MarkAnti-Glial Fibrillary Acidic Protein-PE Antibody, clone GA5 detects level of Glial Fibrillary Acidic Protein & has been published & validated for use in FC.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Quality

Evaluated by flow cytometry using U251 cells

Target description

50 kDa Calculated

Physical form

Protein A purified
Purified mouse monoclonal IgG1 conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Storage and Stability

Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt.

Analysis Note

Control
U251 cells

Legal Information

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Hiroyuki Konishi et al.
The EMBO journal, 39(22), e104464-e104464 (2020-09-23)
Microglia are the principal phagocytes that clear cell debris in the central nervous system (CNS). This raises the question, which cells remove cell debris when microglial phagocytic activity is impaired. We addressed this question using Siglechdtr mice, which enable highly
Dong Woo Kang et al.
The Journal of pathology, 252(3), 304-316 (2020-07-30)
Resistance of glioblastoma to the chemotherapeutic compound temozolomide is associated with the presence of glioblastoma stem cells in glioblastoma and is a key obstacle for the poor prognosis of glioblastoma. Here, we show that phospholipase D1 is elevated in CD44High

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