CD68 is highly glycosylated lysosomal membrane protein with an Mr of 110,000. The CD68 protein belongs to a family of lysosomal glycoprotein (LGP)/plasma membrane shuttling proteins that play a role in endocytosis and/or lysosomal trafficking. CD68 is expressed strongly in cytoplasmic granules, and weakly on the surface of macrophages, monocytes, neutrophils, basophils, and NK cells. CD68 can also be found in the cytoplasm of non-hematopoietic tissues, especially the liver, and renal glomeruli, and tubules (Goyert, 1997).
Specificity
Antibody recognizes Human CD68 antigen.
Immunogen
Lysosomal fraction of human lung macrophages
Application
Research Category Inflammation & Immunology
Research Sub Category Immunoglobulins & Immunology
This Milli-Mark Anti-CD68-FITC Antibody, clone KP1 is validated for use in FC for the detection of CD68.
Quality
Evaluated by flow cytometry using human lymphocytes
Target description
110 kDa (Goyert, 1997)
Physical form
Protein A purified
Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
Storage and Stability
Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.
Analysis Note
Control Human Lymphocytes
Legal Information
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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