AB3040

Anti-Uncoupling Protein 2 Antibody

Chemicon^®, from rabbit

• Sinónimos: UCP2
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• purificado por: affinity chromatography
• reactividad de especies: mouse
• fabricante / nombre comercial: Chemicon^®
• técnicas: ELISA: suitable; western blot: suitable
• Nº de acceso NCBI: NM_003355.2
• Nº de acceso UniProt: P55851
• Condiciones de envío: dry ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: mouse ... Ucp2(22228)

Descripción

Especificidad

Uncoupling Protein 2 (UCP2), mouse. Mouse UCP2 is a 309 amino acid mitochondrial uncoupling protein (Fleury et al. 1997). It is only 59% homologous with UCP1 found in brown adipose tissues. Mouse UCP2 (chromosome 7) has approximately 95% homology with human UCP2 located on chromosome 11 (Fleury et al. 1997). UCP2 has wide tissue distribution in mouse tissues (brain, kidney, liver, brown adipose tissue, heart, and muscle). UCP2 may play a critical role in energy balance, body weight, and thermoregulation (Fleury et al. 1997; Flier & Lowell 1997).

SPECIES REACTIVITIES: The antibody has not yet been tested for cross-reactivity to other species. The sequence used for immunization shows 100% homology in rat, 86% homology in human, porcine, canine and bovine.

Inmunógeno

14 aa peptide sequence near the C-terminus of the mouse UCP2 (Fleury et al. 1997). The peptide has no significant homology with UCP1 or UCP3 (Boss et al. 1997). This peptide is available for blocking as catalog number AG788.

Aplicación

Anti-Uncoupling Protein 2 Antibody is an antibody against Uncoupling Protein 2 for use in ELISA & WB.

Research Category
Metabolism

Research Sub Category
Ion & Transport Channels

Western Blotting: 1-10 μg/mL using Chemiluminescence technique.

ELISA: 1:10,000-1:100,000; using 50-100 ng UCP2 control peptide/well.

Optimal working dilutions must be determined by end user.

Forma física

Affinity purified immunoglobulin. Liquid in PBS, pH 7.4 with 0.1% BSA as stabilizer and 0.02% sodium merthiolate.

Almacenamiento y estabilidad

Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable