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AB1975

Sigma-Aldrich

Anti-Enkephalin, Met Antibody

serum, Chemicon®

Sinónimos:

Anti-PE, Anti-PENK-A

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable

suitability

not suitable for Western blot

UniProt accession no.

P01210

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

rat ... Penk(29237)

General description

Met Enkephalin is an endogenous opioid peptide neurotransmitter found naturally in the brains of many animals, including humans. Methionine enkephalin (Met Enkephalin) is a pentapeptide that appears to enhance immune function at low doses and suppress at high doses. This molecule acts in the central nervous, neuroendocrine, and immune systems. During development of the brain Met Enkephalin is thought to act as a growth factor. Met Enkephalin may be capable of enhancing immune function in cancer or AIDS patients.

Specificity

Met-enkephalin

Immunogen

Met-enkephalin, Hemocyanin conjugate.

Application

Immunohistochemistry (with immunoperoxidase detection *): 48 hour incubation, 4°C.

Spinal cord nerve fibers (rat): 1:2,000-1:4,000.

Immunofluorescence*: overnight incubation, +2-8°C

Duodenum endocrine cells & nerve fibers (pig): 1:2,000

Ileum endocrine cells & nerve fibers μguinea pig): 1:4,000.

*fixative-any cross-linking reagent

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neuroinflammation & Pain

Hormones & Receptors
This Anti-Enkephalin, Met Antibody is validated for use in IH for the detection of Enkephalin.

Target description

0.6 kDa

Linkage

Replaces: AB5026

Physical form

Serum in 0.05% Sodium Azide

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.

Analysis Note

Control
Tested on rat brain/coronal section

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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In the present study, we characterize the antinociceptive effects produced by the chemokine CCL4 in mice. The intraplantar administration of very low doses of CCL4 (0.1-3 pg) produced bilateral antinociception assessed by the unilateral hot-plate test (UHP) without evoking chemotactic responses
K J Dougherty et al.
Neuroscience, 163(3), 909-919 (2009-06-30)
The synthesis enzyme glutamic acid decarboxylase (GAD65 or GAD67) identifies neurons as GABAergic. Recent studies have characterized the physiological properties of spinal cord GABAergic interneurons using lines of GAD67-green fluorescent protein (GFP) transgenic mice. A more complete characterization of their
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Parasites & vectors, 8, 359-359 (2015-07-15)
In vertebrates, the presence of enteric worms can induce structural changes to the alimentary canal impacting on the neuroendocrine system, altering the proper functioning of the gastrointestinal tract and affecting the occurrence and relative density of endocrine cells (ECs). This

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