Saltar al contenido
Merck
Todas las fotos(1)

Documentos clave

AB1518

Sigma-Aldrich

Anti-Neurofibrillary Tangles Antibody

serum, Chemicon®

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización


About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
En este momento no podemos mostrarle ni los precios ni la disponibilidad

origen biológico

rabbit

Nivel de calidad

forma del anticuerpo

serum

tipo de anticuerpo

primary antibodies

clon

polyclonal

reactividad de especies

human

fabricante / nombre comercial

Chemicon®

técnicas

ELISA: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable

Condiciones de envío

dry ice

modificación del objetivo postraduccional

unmodified

Especificidad

Specifically stains neurofibrillary tangles and degenerating plaque neurites in cases of Alzheimer′s disease, Down′s Syndrome and normal aged individuals.

Inmunógeno

Neurofibrillary tangles which were extracted in boiling SDS and purified by sucrose gradient centrifugation.

Aplicación

Anti-Neurofibrillary Tangles Antibody is an antibody against Neurofibrillary Tangles for use in ELISA, WB, IH, IH(P).
Immunohistochemistry on paraffin, vibratome and frozen sections: ≥1:200, ≥1:2,000, respectively.

Western blotting: ≥1:500.

ELISA using immunogen peptide: ≥1:4,000.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases

Forma física

Rabbit antisera with 0.01% thimerosal.

Almacenamiento y estabilidad

Store at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

¿No encuentra el producto adecuado?  

Pruebe nuestro Herramienta de selección de productos.

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Reducing amyloid-related Alzheimer's disease pathogenesis by a small molecule targeting filamin A.
Wang, HY; Bakshi, K; Frankfurt, M; Stucky, A; Goberdhan, M; Shah, SM; Burns, LH
The Journal of Neuroscience null
Milena Penkowa et al.
Journal of neuroscience research, 77(1), 35-53 (2004-06-16)
Transgenic expression of interleukin-6 (IL-6) in the CNS under the control of the glial fibrillary acidic protein (GFAP) gene promoter (GFAP-IL6 mice) induces significant inflammation and neurodegeneration but also affords neuroprotection against acute traumatic brain injury. This neuroprotection is likely
Julio J Ramirez et al.
Behavioural brain research, 216(1), 332-340 (2010-08-24)
Entorhinal cortex neuropathology begins very early in Alzheimer's disease (AD), a disorder characterized by severe memory disruption. Indeed, loss of entorhinal volume is predictive of AD and two of the hallmark neuroanatomical markers of AD, amyloid plaques and neurofibrillary tangles
Milena Penkowa et al.
Journal of neuroscience research, 79(4), 522-534 (2004-12-23)
We examined metallothionein (MT)-induced neuroprotection during kainic acid (KA)-induced excitotoxicity by studying transgenic mice with MT-I overexpression (TgMT mice). KA induces epileptic seizures and hippocampal excitotoxicity, followed by inflammation and delayed brain damage. We show for the first time that
Leslie Vargas-Saturno et al.
The European journal of neuroscience, 48(12), 3514-3533 (2018-11-08)
Understanding endogenous neurogenesis and neuronal replacement to mature circuits is a topic of discussion as a therapeutic alternative under acute and chronic neurodegenerative disorders. Adaptive neurogenic response may result as a result of ischemia which could support long-term recovery of

Questions

Reviews

No rating value

Active Filters

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico