516355

Pentraxin 3/TSG-14, Mouse, Recombinant

• Sinónimos: TSG-14
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• assay: ≥90% (SDS-PAGE)
• Quality Level: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• impurities: <1.0 EU/μg protein Endotoxin
• shipped in: ambient
• storage temp.: −20°C

Descripción

General description

Recombinant, mouse pentraxin 3, consisting of amino acids 18-381 and expressed in NS0-derived murine myeloma cells with a C-terminal His•Tag. Pentraxin 3, a secreted glycoprotein, exhibits a C-terminal Pentraxin domain and a unique N-terminal domain. Its increased expression may enhance the immune response to protect a host from infection.

Biochem/physiol Actions

Functional ELISA: binds rhC1q (5 µg/ml) in the linear range of 0.25-15 µg/ml.

Warning

Toxicity: Standard Handling (A)

Physical form

Lyophilized from 0.2 µm filtered MOPS, NaCl, CaCl₂, BSA.

Reconstitution

Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.

Reconstitute to 100 µg/ml in sterile PBS containing at least 0.1% human or bovine serum albumin.

Other Notes

Dias, A.A.M. et al. 2001. J. Leukocyte Biol.69, 928.
Luchetti, M.M. et al. 2000. Clin. Exp. Immunol.119, 196.
Rovere, P. et al. 2000. Blood96, 4300.
Bottazzi, B. et al. 1997. JBC. 272, 32817.
Goodman A.R. et al. 1996. Cytokine & Growth Factor Rev.7, 191.
Introna, M. et al. 1996. Blood87, 1862.
Altmeyer, A. et al. 1995. J. Biol. Chem.270, 25584.
Lee, G.W. et al. 1993. J. Immunol.150, 1804.
Breviario, F. et al. 1992. JBC.267, 22190.
Lee, T.H. et al. 1990. Mol. Cell. Biol.10, 1982.
Osmand, A.P. et al. 1977. PNAS, USA74, 739.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3