Recombinant human MKK6, amino acids 4-end, fused at the N-terminus to a Mal-E tag
Acciones bioquímicas o fisiológicas
Protein Target: MKK6
Target Sub-Family: STE
Calidad
routinely evaluated by phosphorylation of MBP
Forma física
affinity chromatography on amylose resin beads
Almacenamiento y estabilidad
6 months at -70C
Otras notas
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Información legal
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Proceedings of the National Academy of Sciences of the United States of America, 119(4) (2022-01-26)
Proinflammatory cytokine production by innate immune cells plays a crucial role in inflammatory diseases, but the molecular mechanisms controlling the inflammatory responses are poorly understood. Here, we show that TANK-binding kinase 1 (TBK1) serves as a vital regulator of proinflammatory
Acta crystallographica. Section E, Crystallographic communications, 71(Pt 6), 592-596 (2015-06-20)
Time-of-flight neutron powder diffraction data have been collected from Na2MoO4 and Na2WO4 to a resolution of sin (θ)/λ = 1.25 Å(-1), which is substanti-ally better than the previous analyses using Mo Kα X-rays, providing roughly triple the number of measured reflections with
Acta crystallographica. Section E, Crystallographic communications, 71(Pt 7), 799-806 (2015-08-19)
Time-of-flight neutron powder diffraction data have been measured from ∼90 mol% deuterated isotopologues of Na2MoO4·2H2O and Na2WO4·2H2O at 295 K to a resolution of sin (θ)/λ = 0.77 Å(-1). The use of neutrons has allowed refinement of structural parameters with a precision that varies
Nitric oxide (NO), is a redox-active, endogenous signalling molecule involved in the regulation of numerous processes. It plays a crucial role in adaptation and tolerance to various abiotic and biotic stresses. In higher plants, NO is produced either by enzymatic
Journal of cellular physiology, 232(2), 355-362 (2016-10-31)
Diabetic kidney disease (DKD) is the major cause of end stage renal disease. Sodium tungstate (NaW) exerts anti-diabetic and immunomodulatory activities in diabetic animal models. Here, we used primary cultures of renal proximal tubule epithelial cells derived from type-2-diabetic (D-RPTEC)
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