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Merck

137132

SAFC

SyntheChol® PLANT-DERIVED CHOLESTEROL

EMPROVE® EXPERT

Fabricación farmacéutica

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About This Item

UNSPSC Code:
12352100

biological source

synthetic

Quality Level

product line

EMPROVE® EXPERT

bp

200 °C

mp

141 °C

solubility

>0.001 g/L

density

1.05 g/cm3 at 20 °C

bulk density

260 kg/m3

suitability

suitable for manufacturing use

shipped in

dry ice

storage temp.

−20°C (−15°C to −25°C)

General description

Our SAFC® portfolio of high-quality products for biopharmaceutical processing withstands strict quality control procedures and is produced according to MQ-500 requirements as defined by the M-Clarity program.

M-Clarity Program

As part of our EMPROVE® Program, our raw materials are offered with EMPROVE® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

Biochem/physiol Actions

Major component of all biological membranes; ~25% of total brain lipid is cholesterol.

Preparation Note

Synthesized from material of non-animal origin.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
SyntheChol is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

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Scott B Widenmaier et al.
Cell, 171(5), 1094-1109 (2017-11-18)
Cholesterol is a critical nutrient requiring tight constraint in the endoplasmic reticulum (ER) due to its uniquely challenging biophysical properties. While the mechanisms by which the ER defends against cholesterol insufficiency are well described, it remains unclear how the ER senses

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