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Merck

1.08694

SAFC

Deviron® 13-S9

Detergent, EMPROVE® EXPERT

Fabricación farmacéutica

Sinónimos:

Alcohols, C11-15-secondary, ethoxylated

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About This Item

Quality Level

product line

EMPROVE® EXPERT

application(s)

pharma/biopharma processes

storage temp.

15-25°C

General description

Detergents, such as non-ionic surfactants, are used in biomanufacturing processes for a variety of applications including viral inactivation and cell lysis. Detergent-mediated viral inactivation is widely used in multiple biotherapeutic production processes to ensure meeting regulatory requirements for viral safety.

Our SAFC portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

As part of our EMPROVE® Program, our raw materials are offered with EMPROVE® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.

Our comprehensive portfolio of downstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

We offer a range of high quality critical raw materials plus the documentation and expertise to help our customers meet stringent regulatory requirements. Our SAFC portfolio of high-quality products withstands strict quality control procedures.

Application

REACH compliantdetergent used in viral inactivation or cell lysis.

Packaging

1.08694.1000 / 1L / Glass bottle

1.08694.2500 / 2.5L / Glass bottle

1.08694.9025 / 25L / PE container

Legal Information

DEVIRON is a registered trademark of Merck KGaA, Darmstadt, Germany
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

469.4 °F - open cup

flash_point_c

243 °C - open cup


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Artículos

En esta página se describen consideraciones clave para la lisis celular y cómo se puede utilizar la combinación de una concentración salina elevada y una endonucleasa tolerante a la sal para aumentar la concentración del vector y la infectividad durante la fabricación de vectores AAV.

This page describes key considerations for cell lysis and how the combination of a high salt concentration and a salt tolerant endonuclease can be used to increase vector titer and infectivity during AAV vector manufacturing.

Contenido relacionado

The use of Benzonase® endonuclease can significantly reduce the levels of DNA by more than 100,000-fold while also reducing viscosity and protecting downstream equipment from DNA fouling. However, optimization strategies and DoE are critical when it comes to reducing DNA in your process. Setting up a DoE for your Benzonase® endonuclease application can help you find the optimal operation conditions that deliver the required DNA clearance from your process.

Learn more on mAb downstream processing, more specifically virus inactivation and the relevant associated products.

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

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