09-814
Anti-dimethyl-Arginine Antibody, asymmetric (ASYM25)
serum, from rabbit
Sinónimos:
dimethyl-arginine, asymmetric
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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origen biológico
rabbit
Nivel de calidad
forma del anticuerpo
serum
tipo de anticuerpo
primary antibodies
clon
polyclonal
reactividad de especies
mouse
reactividad de especies (predicha por homología)
rat (based on 100% sequence homology), human (based on 100% sequence homology)
técnicas
western blot: suitable
Condiciones de envío
wet ice
modificación del objetivo postraduccional
unmodified
Descripción general
Asymmetrical dimethlarginine (ADMA) is an endogenous, L-arginine metabolite arising from the proteolysis of methylated arginine containing proteins and is a known inhibitor of nitric oxide synthase (NOS). In various studies, ADMA has been observed as having a regulatory role in cell motility and the actin cytoskeleton. Elevated levels of ADMA are associated with sporadic FSGS, coronary artery disease, hypertension, peripheral arterial occlusive disease, obesity, stroke, preeclampsia, and cardiovascular mortality/morbidity in patients with diabetic nephropathy.
Especificidad
This antibody recognizes dimethylated arginines.
Inmunógeno
KLH-conjugated linear peptide containing asymmetric dimethyl-arginine-glycine repeats.
Aplicación
Detect dimethyl-Arginine using this Anti-dimethyl-Arginine Antibody, asymmetric (ASYM25) validated for use in WB.
Calidad
Evaluated by Western Blot in PRMT1 treated and untreated MEF cell lysates.
Western Blot Analysis: 1:1,000 dilution of this antibody detected dimethyl-Arginine on 10 µg of PRMT1 treated and untreated MEF cell lysates.
Western Blot Analysis: 1:1,000 dilution of this antibody detected dimethyl-Arginine on 10 µg of PRMT1 treated and untreated MEF cell lysates.
Descripción de destino
Multiple. This antibody detects proteins containing asymmetrical dimethylated arginines.
Nota de análisis
Control
PRMT1 treated and untreated MEF cell lysates
PRMT1 treated and untreated MEF cell lysates
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Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
WGK 1
Certificados de análisis (COA)
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