GST-fusion protein corresponding to residues 519-939 of human IQGAP2, purified from E. coli
Application
Anti-IQGAP2 Antibody, clone BB9 detects level of IQGAP2 & has been published & validated for use in IP & WB.
Quality
routinely evaluated by immunoblot on RIPA lysates from HepG2 cells
Target description
180kDa
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
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Journal of immunology (Baltimore, Md. : 1950), 188(12), 6135-6144 (2012-05-11)
The Ras GTPase-activating-like protein IQGAP1 is a multimodular scaffold that controls signaling and cytoskeletal regulation in fibroblasts and epithelial cells. However, the functional role of IQGAP1 in T cell development, activation, and cytoskeletal regulation has not been investigated. In this
Paclitaxel induces pyroptosis by inhibiting the volumea?`sensitive chloride channel leucinea?`rich repeata?`containing 8a in ovarian cancer cells.
Proteins of the IQGAP family have been identified as candidate effectors for the Rho family of GTPases; however, little is known about their cellular functions. The domain structures of IQGAP family members make them excellent candidates as regulators of the
Metabolic adaptation to a disruption in oxygen supply during myocardial ischemia and reperfusion is underpinned by temporal and quantitative changes in the cardiac proteome.
Xin Li,Fatih Arslan,Yan Ren,Sunil S Adav,Kian Keong Poh,Vitaly Sorokin,Chuen Neng Lee et al.
Under hypoxia, tumor cells produce a secretion that modulates their microenvironment to facilitate tumor angiogenesis and metastasis. Here, we observed that hypoxic or reoxygenated A431 carcinoma cells exhibited enhanced angiogenic and metastatic potential such as reduced cell-cell and cell-extracellular matrix
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